不同贮藏条件对桃仁饮片酸败度及苦杏仁苷含量的影响(1)
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[摘要] 目的 考察不同贮藏条件对对桃仁饮片酸败度及苦杏仁苷含量的影响，为进一步开展桃仁贮藏养护方法的研究奠定基础。 方法 以不同贮藏条件分组贮存桃仁药材2年，每隔4或6个月检查各组桃仁饮片酸败度，并测定苦杏仁苷含量。 结果 在两年贮藏期间，随着贮藏时间的推移，各贮藏条件下，桃仁饮片的酸值和羰基值均呈现上升趋势，而苦杏仁苷含量呈现明显的下降趋势。以真空包装或低温条件下贮藏的桃仁饮片其酸败程度较轻，苦杏仁苷含量较为稳定。 结论 根据酸败度及苦杏仁苷含量变化规律，桃仁饮片宜以真空包装，在低温条件下贮藏。
[关键词] 桃仁；贮藏条件；酸败度；苦杏仁苷
[中图分类号] R282.6 [文献标识码] A [文章编号] 1673-7210(2012)02(b)-0013-03
The influence on the rancidity and amgydalin content of Persicae semen in different storage conditions
LAN Zhiqiong1 LU Xianming1 ZHANG Lijuan1 SUN Xuemei2 JIANG Guihua1
1.State Key Laboratory Breeding Base of Systematic Research of Development and Utilization of Chinese Medicine Resources, School of Pharmacy, Chengdu University of TCM, Sichuan Province, Chengdu 611137, China; 2.Shijiazhuang No.4 Pharmacentical Co.Ltd., Hebei Province, Shijiazhuang 050035, China
[Abstract] Objective To study the rancidity and amygdatin content of Persicae semen in different storage conditions, so as to lay a firm foundation for the futher research on storage method of Persicae semen. Methods Persicae semen were storaged in diferent condition for two years. Rancidities and amygdatin contents in Persicae semen were tested every four or six months in the storing period. Results The acid value and arbonyl group value of Persicae semen which had storaged in diffrent conditions were all rising and the amgydalin contents were all falling as time went by for two years. The rancidity change of Persicae semen with vacuum package or in the low temperature was less influenced and the amgydalin content was more stable. Conclusion Persicae semen should be stored at low temperature with vacuum package according the change rule of rancidity and amgydalin content.
[Key words] Persicae semen; Storage conditions; Rancidity; Amygdatin
桃仁为蔷薇科植物桃Prunus persica(L.)Batsch或山桃Prunus davidiana(Carr.)Franch.的干燥成熟种子[1]，为常用中药，具有活血祛瘀、润肠通便之功效，用于经闭、痛经、症瘕痞块、跌扑损伤、肠燥便秘，是妇科要药[2]。
同其他富含油脂的果实种子类饮片一样，桃仁在贮藏中极易发生泛油、虫蛀、霉变、变色等变质现象。但是，目前桃仁的研究工作主要集中在化学成分及药理学领域，贮藏养护的相关研究甚少，亟待加强这方面的研究工作，保障临床用药的安全性、有效性和稳定性。桃仁等易泛油，饮片在贮藏中易产生酸败现象，酸败不仅导致药材产生一定的毒性，同是还影响饮片中有效组分油酸和亚油酸的含量，故酸败度是评价桃仁等易泛油饮片质量的重要指标；苦杏仁苷在《中国药典》2005年版一部[1]196-197、《中药学》[2]和日本汉方制剂规格试验法[3]中 ......
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