置入疗法治疗颈动脉狭窄的临床研究(1)
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[摘要] 目的 研究置入疗法在治疗颈动脉狭窄的临床疗效及应用价值。 方法 将我院2009年3月～2010年3月治疗的84例颈动脉狭窄患者随机分为对照组和观察组，各42例，对照组使用临床应用率较高的颈动脉内膜切除术进行治疗，观察组使用置入疗法治疗。将两组患者的疗效、并发症、残余狭窄率以及术后复发率等临床数据进行比较，并进行统计学分析。 结果 对照组手术总有效率为97.6%，残余狭窄率为32.3%，观察组手术总有效率为100.0%，残余狭窄率为27.8%，其临床观察指标观察组均优于对照组，且差异均有统计学意义(均P < 0.05)。 结论 置入疗法治疗颈动脉狭窄较颈动脉内膜切除术具有明显的优势，有重要的临床应用价值。
[关键词] 置入疗法；颈动脉内膜切除术；颈动脉狭窄
[中图分类号] R653 [文献标识码] A [文章编号] 1673-7210(2012)02(b)-0045-02
Clinical research on implant therapy treatment for carotid artery stenosis
CHI Jinchen LI Qingzhu LI Wei
The People′s Hospital of Linqing City, Shandong Province, Linqing 252600, China
[Abstract] Objective To study clinical effectiveness and application value of implant therapy treatment for carotid artery stenosis. Methods 84 cases of patients with carotid artery stenosis from March 2009 to March 2010 in our hospital were randomly divided into control group and observation group, with each group of 42 cases, the control group was used the carotid endarterectomy, and the observation group was used the implant therapy. The effective rate of operation, complication, residual stricture rate, efficacy and postoperative clinical data comparison recurrence rate, etc were compared and analyzed in the two groups. Results The effective rate of the operation in the control group was 97.6%, residual stricture rate was 32.3%, the effective rate of the operation in the observation group was 100.0%, residual stricture rate was 27.8%; the other clinical data of observation group were better than those of control group, there were significant differences (all P < 0.05). Conclusion Implant therapy treatment for carotid artery stenosis has obvious advantages than carotid endarterectomy, and has important value in clinical application.
[Key words] Implant therapy; Carotid endarterectomy; Carotid artery stenosis
颈动脉狭窄已成为当今临床的多发病和常见病，多发于60岁以上的老年人，可直接导致患者死亡或严重的神经功能障碍。据相关资料显示，由颈动脉狭窄而导致脑卒中居致死疾病的第3位。临床上主要采用颈动脉内膜切除术进行治疗，该法虽疗效确切，但手术对于部分合并心血管疾病及老年患者的风险性很高[1]。近年来，临床开始使用微创的颈动脉置入疗法进行治疗，取得了理想的效果。我院对植入性疗法的适应证、疗效、安全性、并发症、复发率及患者满意率进行了研究，进一步证实了置入疗法的临床价值。
1 资料与方法
1.1 一般资料
2009年3月～2010年3月在我院治疗颈动脉狭窄患者共84例，其中，男56例，女28例；年龄59～71岁，平均63.6岁；反复短暂性脑缺血发作26例，陈旧性脑梗死58例。患者血管造影显示：颈总动脉狭窄6例，颈总动脉合并颈内动脉狭窄4例，单纯颈内动脉狭窄72例，其中，双侧狭窄32例，单侧狭窄40例，患者颈动脉狭窄均在50.3%以上。合并症：慢性肺气肿5例，冠心病12例，高脂血症14例 ......
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