不稳定心绞痛危险分层与心脑血管病的相关性分析(1)
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[摘要] 目的 探讨心绞痛危险分层与心脑血管病的相关性。 方法 对2010年1月～2011年5月来我院诊治的180例不同危险分层的心绞痛患者，分别进行QRS波碎裂、缺血修饰蛋白(IMA)、钠尿肽(BNP)、动脉粥样斑块及内膜-中膜厚度(IMT)的检测，利用冠脉造影对冠脉病变支数和冠脉狭窄程度进行检测，以及经颅多普勒(TCD)检查。 结果 与低危组(21.7%)相比，中危组(43.3%)、高危组(65.0%)出现QRS波碎裂的发生率明显增多(P < 0.05)。与低危组相比，中、高危组IMA水平明显升高(P < 0.05)。与低危组相比，中、高危组钠尿肽BNP明显提高(P < 0.05)。随着危险分层的增高，冠脉动脉病变支数逐渐由单支病变转变为多支病变，冠脉狭窄程度逐渐增加，TCD检查异常率升高。 结论 心绞痛危险分层越高，发生心脑血管病的几率就越高。
[关键词] 心绞痛；危险分层；心脑血管病；相关性
[中图分类号] R541.4 [文献标识码] A [文章编号] 1673-7210(2012)08(b)-0050-03
Correlation analysis of the risk stratification of unstable angina with cardio-cerebrovascular disease
YUAN Muxiang
The First People′s Hospital of Xiantao City, Hubei Province, Xiantao 433000, China
[Abstract] Objective To study the correlation of the risk stratification of unstable angina with cardio-cerebrovascular disease. Methods 180 angina patients with different risk stratification during the period from January 2010 to May 2011 in our hospital were measured respectively QRS complex fragmentation, ischemia-modified protein (IMA), natriuretic peptide (BNP), atherosclerotic plaque and intima-media thickness (IMT). The coronary lesions and coronary stenosis were detected by coronary angiography, TCD measures were assayed by transcranial Doppler examination. Results Compared with the low risk group (21.7%), the QRS complex fragmentation was significantly increased in middle and high risk groups (43.3% and 65.0%) (P < 0.05). Compared with the low risk group, the IMA levels increased significantly in middle and high risk groups (P < 0.05). Compared with the low risk group , the natriuretic peptide BNP significantly increased in middle and high risk groups (P < 0 ......
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