超声造影在良恶性卵巢肿瘤鉴别诊断中的价值(1)
[摘要] 目的 观察卵巢肿瘤在普通多普勒和超声造影中的表现，分析评价超声造影对卵巢肿瘤良恶性的诊断价值。 方法 选取2013年1月～2015年1月在海南省人民医院行常规超声检查诊断为卵巢肿瘤患者64例为研究对象，所有患者于术前行超声造影，结合术后病理结果，采用ROC曲线下面积比较分析两种检测方法的灵敏度。 结果 病理检查结果显示64例卵巢肿瘤中良性37例，恶性27例。卵巢良、恶性肿瘤的造影强化特点存在明显差异。37例卵巢良性肿瘤中，35例造影剂缓慢强化，27例卵巢恶性肿瘤均表现为造影剂快速强化。与卵巢良性肿瘤相比，卵巢恶性肿瘤内造影强化的始增时间早，达峰时间早，灌注强度高，造影强化的时间-强度曲线上升支、下降支陡直。普通多普勒超声对恶性卵巢肿瘤检出的灵敏度为44.44%，通过超声造影检出恶性卵巢肿瘤的灵敏度为74.07%。普通多普勒ROC下面积为0.598，超声造影ROC下面积为0.723。 结论 超声造影有助于更准确地评价肿瘤内的血流信息，对卵巢良、恶性肿瘤的鉴别诊断及卵巢肿瘤的早期诊断有重要的参考价值。
[关键词] 超声造影；卵巢肿瘤；良恶性；鉴别诊断
[中图分类号] R445.1；R737.31 [文献标识码] A [文章编号] 1673-7210(2016)01(a)-0117-04
Significance of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant ovarian tumors
LI Zaihong1 JING Xiangxiang1 YOU Jia1 ZHOU Qiaomiao2 WANG Shengtan2 LIU Fujin3 HAN Lizhen4
1.Department of Ultrasonography， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 2.Department of Obstetrics and Gynecology， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 3.Department of Pathology， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 4.Department of Medical Record Statistics， Hainan People's Hospital， Hainan Province， Haikou 570311， China
[Abstract] Objective To observe the appearance of ovarian tumors in ultrasound and contrast-enhanced ultrasonography， then to analyze and evaluate the diagnostic value of contrast-enhanced ultrasonography in benign and malignant ovarian tumors. Methods Sixty-four patients with ovarian tumors diagnosed by normal ultrasound in Hainan People's Hospital from January 2013 to January 2015 were chosen as research objects. All patients were given contrast-enhanced ultrasonography before operation， combined with postoperative pathologic results， the sensitivity of the two methods was compared by ROC of the area under the curve. Results The pathologic results showed that there were 37 cases of benign tumor and 27 cases of malignant tumor among 64 cases of ovarian tumors. There were significant differences of the enhanced characteristics between benign and malignant ovarian tumors， among 37 cases of benign tumor， 35 cases showed contrast agent enhanced slowly. All of 27 cases of malignant tumor showed contrast agent enhanced rapidly. Compared with the benign tumors， in malignant ovarian tumors， the enhancement appeared earlier and reached to the top rapidly， and their contrast-enhanced curves including the ascending and descending branches were steep. The sensitivity rate of malignant tumor detected by conventional ultrasound was 44.44%， which of malignant tumor detected by contrast-enhanced ultrasonography was 74.07%. The ROC area of conventional ultrasound was 0.598， which of contrast-enhanced ultrasonography was 0.723. Conclusion The contrast-enhanced ultrasonography allows a more complete display of the vascular patterns in ovarian tumors， which plays an important role in differential diagnosis and early diagnosis of ovarian tumors., 百拇医药(李载红 景香香 游佳 周俏苗 王圣坦 刘富金 韩丽珍)
[关键词] 超声造影；卵巢肿瘤；良恶性；鉴别诊断
[中图分类号] R445.1；R737.31 [文献标识码] A [文章编号] 1673-7210(2016)01(a)-0117-04
Significance of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant ovarian tumors
LI Zaihong1 JING Xiangxiang1 YOU Jia1 ZHOU Qiaomiao2 WANG Shengtan2 LIU Fujin3 HAN Lizhen4
1.Department of Ultrasonography， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 2.Department of Obstetrics and Gynecology， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 3.Department of Pathology， Hainan People's Hospital， Hainan Province， Haikou 570311， China； 4.Department of Medical Record Statistics， Hainan People's Hospital， Hainan Province， Haikou 570311， China
[Abstract] Objective To observe the appearance of ovarian tumors in ultrasound and contrast-enhanced ultrasonography， then to analyze and evaluate the diagnostic value of contrast-enhanced ultrasonography in benign and malignant ovarian tumors. Methods Sixty-four patients with ovarian tumors diagnosed by normal ultrasound in Hainan People's Hospital from January 2013 to January 2015 were chosen as research objects. All patients were given contrast-enhanced ultrasonography before operation， combined with postoperative pathologic results， the sensitivity of the two methods was compared by ROC of the area under the curve. Results The pathologic results showed that there were 37 cases of benign tumor and 27 cases of malignant tumor among 64 cases of ovarian tumors. There were significant differences of the enhanced characteristics between benign and malignant ovarian tumors， among 37 cases of benign tumor， 35 cases showed contrast agent enhanced slowly. All of 27 cases of malignant tumor showed contrast agent enhanced rapidly. Compared with the benign tumors， in malignant ovarian tumors， the enhancement appeared earlier and reached to the top rapidly， and their contrast-enhanced curves including the ascending and descending branches were steep. The sensitivity rate of malignant tumor detected by conventional ultrasound was 44.44%， which of malignant tumor detected by contrast-enhanced ultrasonography was 74.07%. The ROC area of conventional ultrasound was 0.598， which of contrast-enhanced ultrasonography was 0.723. Conclusion The contrast-enhanced ultrasonography allows a more complete display of the vascular patterns in ovarian tumors， which plays an important role in differential diagnosis and early diagnosis of ovarian tumors., 百拇医药(李载红 景香香 游佳 周俏苗 王圣坦 刘富金 韩丽珍)