BNDF调控SIRT1/PGC—1α通路拮抗Aβ25~35诱导的神经元细胞氧化损伤(4)
综上所述,BDNF预处理能够减轻Aβ25~35诱导的神经元细胞凋亡,这对临床上采用补充大脑外源性BDNF治疗AD患者提供了理论支持。
[参考文献]
[1] Amariglio RE,Donohue MC,Marshall GA,et al. Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia:the Alzheimer's Disease Cooperative Study Cognitive Function Instrument [J]. JAMA Neurol ......
您现在查看是摘要页,全文长 2744 字符。
[参考文献]
[1] Amariglio RE,Donohue MC,Marshall GA,et al. Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia:the Alzheimer's Disease Cooperative Study Cognitive Function Instrument [J]. JAMA Neurol ......
您现在查看是摘要页,全文长 2744 字符。