[摘要] 经皮冠脉内介入治疗(PCI)目前已成为冠心病的重要治疗方式。但是，术后发生的支架内再狭窄(ISR)及晚期的血栓形成(LST)是当前临床上亟待解决的问题。研究发现，支架内新生动脉粥样硬化(ISNA)是造成ISR及LST的重要原因。对于ISNA的预防和治療是当前提高冠脉内支架远期效果的切入点。本文主要针对支架内新生动脉粥样硬化的病理机制及其中西医的防治进行论述。

    [关键词] 冠心病；支架内新生动脉粥样硬化；中西医；研究

    [中图分类号] R259 [文献标识码] A [文章编号] 1673-7210(2017)08(a)-0047-04

    [Abstract] Percutaneous coronary intervention has become the important means on the therapy of coronary heart disease. But， the current clinical problems solved are postoperative restenosis and late stent thrombos is which can cause serious adverse cardiovascular events. Studies have found that in-stent neoatherosclosis is an important reason of ISR and LST. For the prevention and treatment of ISNA is the entry point to improve the long-term effect of coronary stent at present. In this paper ......