血管内低频高能超声消融术对动脉粥样硬化斑块的治疗影响(1)
[摘要] 目的 研究動脉粥样硬化斑块患者采取血管内低频高能超声消融术治疗的临床效果。 方法 回顾性分析北方学院附属第一医院2015年8月～2017年3月收治的动脉粥样硬化斑块患者64例的临床资料，根据治疗方法将其分为两组，研究组(32例)采取血管内低频高能超声消融术，对照组(32例)采取经皮冠状动脉腔内血管成形术，比较两组临床治疗效果、并发症及复发情况。 结果 治疗前两组狭窄程度比较，差异无统计学意义(P > 0.05)，治疗后两组狭窄程度均明显降低，且研究组狭窄程度低于对照组，差异有高度统计学意义(P < 0.01)；研究组球囊压力、扩张时间低于对照组，差异有高度统计学意义(P < 0.01)。治疗前两组运动实验结果比较，差异无统计学意义(P > 0.05)，治疗后两组明显改善，且研究组诱发心绞痛时间、ST段下降幅度高于对照组，ST段下降时间低于对照组，差异有高度统计学意义(P < 0.01)。研究组总有效率高于对照组，并发症发生率、复发率低于对照组，差异有统计学意义(P < 0.05)。治疗前两组心功能分级差异无统计学意义(P > 0.05)，治疗后发现研究组心功能Ⅰ、Ⅱ级比例高于对照组，差异有高度统计学意义(P < 0.01)。 结论 动脉粥样硬化斑块患者采取血管内低频高能超声消融术治疗效果更好，有效改善患者冠状动脉狭窄程度，促进心功能恢复正常，避免并发症以及复发，缓解心绞痛症状，促进病情快速稳定。
[关键词] 血管内低频高能超声消融术；动脉粥样硬化斑块；血管成形术；临床价值
[中图分类号] R543 [文献标识码] A [文章编号] 1673-7210(2018)07(a)-0079-05
Effect of intravascular low frequency and high energy ultrasound ablation on atherosclerotic plaque
ZHAO Hongmei WANG Ying SONG Aixia LI Linru XU Xuexia LIU Xingliang
Third Department of Internal Medicine-Neurology， First Affiliated Hospital of Hebei North University， Hebei Province， Zhangjiakou 075000， China
[Abstract] Objective To study the clinical effect of intravascular low frequency and high energy ultrasound ablation for atherosclerotic plaque patients. Methods From August 2015 to March 2017， the clinical data of 64 patients with atherosclerotic plaque in the First Affiliated Hospital of Hebei North University were retrospectively analyzed， and they were divided into two groups according to the treatment method， the study group was given intravascular low frequency and high energy ultrasound ablation， the control group was given percutaneous transluminal coronary angioplasty. The clinical effect， complication and recurrence of two groups were compared. Results Before the treatment， the stenosis degree in two groups was compared， the difference was not statistically significant (P > 0.05)， after the treatment， the stenosis degree in two group reduced significantly， and this in study group was lower than control group， the differences were statistically significant (P < 0.01)； the balloon pressure and dilation time in study group were lower than those in control group， the differences were statistically significant (P < 0.01). Before the treatment， experiment sport results in two groups were compared， the difference was not statistically significant (P > 0.05)； after treatment， two groups were improved statistically， and the time of angina pectoris and ST segment in study group decreased more significantly than control group， the differences were statistically significant (P < 0.01). The total effective rate in study group was higher than control group， the complication rate and recurrence rate in study group were lower than control group， the differences were statistically significant (P < 0.05). Before the treatment， the heart function classification in two groups were compared， the difference was not statistically significant (P > 0.05)； after the treatment， the ratio of cardiac function Ⅰ and Ⅱ in study group was higher than control group， the difference was statistically significant (P < 0.01). Conclusion Patients with atherosclerotic plaque are better treated with intravascular low frequency and high energy ultrasound ablation will have better effects， it can effectively improve the degree of coronary artery stenosis in patients， promote cardiac function to return to normal， avoid complications and recurrence， alleviate the symptoms of angina pectoris， promote the rapid and stable condition， provide protection for the prognosis., 百拇医药(赵红梅 王颖 宋爱霞 李林儒 徐雪霞 刘星亮)
[关键词] 血管内低频高能超声消融术；动脉粥样硬化斑块；血管成形术；临床价值
[中图分类号] R543 [文献标识码] A [文章编号] 1673-7210(2018)07(a)-0079-05
Effect of intravascular low frequency and high energy ultrasound ablation on atherosclerotic plaque
ZHAO Hongmei WANG Ying SONG Aixia LI Linru XU Xuexia LIU Xingliang
Third Department of Internal Medicine-Neurology， First Affiliated Hospital of Hebei North University， Hebei Province， Zhangjiakou 075000， China
[Abstract] Objective To study the clinical effect of intravascular low frequency and high energy ultrasound ablation for atherosclerotic plaque patients. Methods From August 2015 to March 2017， the clinical data of 64 patients with atherosclerotic plaque in the First Affiliated Hospital of Hebei North University were retrospectively analyzed， and they were divided into two groups according to the treatment method， the study group was given intravascular low frequency and high energy ultrasound ablation， the control group was given percutaneous transluminal coronary angioplasty. The clinical effect， complication and recurrence of two groups were compared. Results Before the treatment， the stenosis degree in two groups was compared， the difference was not statistically significant (P > 0.05)， after the treatment， the stenosis degree in two group reduced significantly， and this in study group was lower than control group， the differences were statistically significant (P < 0.01)； the balloon pressure and dilation time in study group were lower than those in control group， the differences were statistically significant (P < 0.01). Before the treatment， experiment sport results in two groups were compared， the difference was not statistically significant (P > 0.05)； after treatment， two groups were improved statistically， and the time of angina pectoris and ST segment in study group decreased more significantly than control group， the differences were statistically significant (P < 0.01). The total effective rate in study group was higher than control group， the complication rate and recurrence rate in study group were lower than control group， the differences were statistically significant (P < 0.05). Before the treatment， the heart function classification in two groups were compared， the difference was not statistically significant (P > 0.05)； after the treatment， the ratio of cardiac function Ⅰ and Ⅱ in study group was higher than control group， the difference was statistically significant (P < 0.01). Conclusion Patients with atherosclerotic plaque are better treated with intravascular low frequency and high energy ultrasound ablation will have better effects， it can effectively improve the degree of coronary artery stenosis in patients， promote cardiac function to return to normal， avoid complications and recurrence， alleviate the symptoms of angina pectoris， promote the rapid and stable condition， provide protection for the prognosis., 百拇医药(赵红梅 王颖 宋爱霞 李林儒 徐雪霞 刘星亮)