代谢组学在眼科中的研究进展
[40] Friedman DS，O′Colmain BJ，Munoz B，et al. Prevalence of age-related macular degeneration in the United States [J]. Arch Ophthalmol，2004，122：564-572.
[41] Laíns I，Kelly RS，Miller JB，et al. Human plasma meta-bolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers [J]. Ophthalmology，2018，125(2)：245-254.
[42] Laíns I，Duarte D，Barros AS，et al. Urine Nuclear Magnetic Resonance (NMR) metabolomics in age-related macular degeneration [J]. J Proteome Res，2019，18(3)：1278-1288.
[43] Osborn MP，Park Y，Parks MB，et al. Metabolome-wide association study of neovascular age-related macular degeneration [J]. PLoS One，2013，27(8)：72737.
[44] Bocca C，Kouassi Nzoughet J，et al. A plasma metabolomic signature involving purine metabolism in human optic atrophy 1 (OPA1)-related disorders [J]. Invest Ophthalmol Vis Sci，2018，59(1)：185-195.
[45] Chao de la Barca JM，Simard G，Amati-Bonneau P，et al. The metabolomic signature of Leber′s hereditary optic neuropathy reveals endoplasmic reticulum stress [J]. Brain，2016，139(11)：2864-2876.
(收稿日期：2019-08-20 本文編辑：李亚聪), 百拇医药(赵黎 李青松 缪晚虹)
[41] Laíns I，Kelly RS，Miller JB，et al. Human plasma meta-bolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers [J]. Ophthalmology，2018，125(2)：245-254.
[42] Laíns I，Duarte D，Barros AS，et al. Urine Nuclear Magnetic Resonance (NMR) metabolomics in age-related macular degeneration [J]. J Proteome Res，2019，18(3)：1278-1288.
[43] Osborn MP，Park Y，Parks MB，et al. Metabolome-wide association study of neovascular age-related macular degeneration [J]. PLoS One，2013，27(8)：72737.
[44] Bocca C，Kouassi Nzoughet J，et al. A plasma metabolomic signature involving purine metabolism in human optic atrophy 1 (OPA1)-related disorders [J]. Invest Ophthalmol Vis Sci，2018，59(1)：185-195.
[45] Chao de la Barca JM，Simard G，Amati-Bonneau P，et al. The metabolomic signature of Leber′s hereditary optic neuropathy reveals endoplasmic reticulum stress [J]. Brain，2016，139(11)：2864-2876.
(收稿日期：2019-08-20 本文編辑：李亚聪), 百拇医药(赵黎 李青松 缪晚虹)