[摘要] 胆囊癌为临床常见胆道系统恶性肿瘤，恶性程度较高。多数患者早期症状不典型，确诊时已处于晚期，往往需行根治性切除术，但术后仍可能出现较高复发率。影响胆囊癌手术预后的因素包括：侵袭深度，组织学分级，淋巴及周围神经浸润和淋巴结转移。而影响胆囊癌预后的一个重要因素为淋巴转移，其分子机制目前仍不甚清楚，故需临床深入分析胆囊癌淋巴转移发生机制。现就国内外临床针对胆囊癌淋巴转移相关分子机制研究现状进行综述，以期为相关实践、研究提供参考依据。

    [关键词] 胆囊癌;淋巴转移;机制;综述

    [中图分类号] R966 [文献标识码] A [文章编号] 1673-7210(2020)03(c)-0033-04

    [Abstract] Gallbladder cancer is a common clinical malignant tumor of the biliary system with a high degree of malignancy. For most patients， symptoms are not typical in early stage and the diagnosis has been in the late stage. So radical resection is always needed. However ......