[摘要]牙侵蚀是指牙体硬组织在无细菌参与的化学作用下的不可逆性丧失，胃食管反流病是常见的胃肠道紊乱性疾病，是牙侵蚀主要的病因之一。本文主要就牙侵蚀的病因、胃食管反流病导致的牙侵蚀机制，牙侵蚀的临床表现，牙侵蚀的预防和治疗等研究进展作一综述。阐明了牙侵蚀是胃食管反流病食管外最重要的表现之一，其诊治需要多科的共同协作，早期诊断胃食管反流病并通过改变生活方式和药物来抑制酸反流，对预防牙侵蚀的发生和干预牙矿质的进一步丢失和损伤极为重要。

    [关键词]牙侵蚀；胃食管反流病；唾液流速

    [中图分类号]R 781.2[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.03.021

    Relationship between dental erosion and gastroesophageal reflux diseaseHuang He1, Fa Yonghong2, Yang Yongjin2, Cai Xingwei2.(1. Graduate Academy of Liaoning Medical College, Jinzhou 121000, China; 2. Dept. of Stomatology, The Second Artillery General Hospital of Chinese People’s Liberation Army, Beijing 100088, China)

    [Abstract]Dental erosion is the irreversible loss of dental hard tissue by chemical process in the absence of bacteria. Gastroesophageal reflux disease(GERD)is a common gastrointestinal disturbance disease, which considered to be one of the main causes to dental erosion. This review aimed to explore the pathogenesis and mechanism of dental erosion, in addition to explain the clinical manifestation, prevention and treatment of dental erosion. Dental erosion is considered to be one of the most important extra-oesophageal manifestations in patients with GERD. The diagnosis and treatment of dental erosion need to coordinate the department of digestive and the department of stomatology. Early diagnosis of GERD and suppress acid reverse flow through the lifestyle changes and drugs, and prevent dental erosion and further loss of teeth mineral and damage are very important. ......