[摘要]脱乙酰壳多糖生物材料尽管具有良好的生物相容性，但其作为牙周组织工程支架材料时也有自身的局限和不足。本文就牙周组织工程、脱乙酰壳多糖、脱乙酰壳多糖牙周组织工程支架等研究进展作一综述。

    [关键词]牙周病；牙周组织；牙周组织工程；脱乙酰壳多糖；支架；牙周膜细胞

    [中图分类号]R 783.1[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.04.016

    Application of chitosan scaffolds in periodontal tissue engineeringZhang Qinghong1, Liang Xing2.(1. Dept. of Prosthodontics, The Affiliated Stomatological Hospital of Medical College, Zhejiang University, Hangzhou 310006, China; 2. Dept. of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China)

    [Abstract]Although chitosan possesses excellent biocompatibility, there are some disadvantages when it is used in periodontal tissue engineering. This present article is to review the higher researching value and better promising clinical utilization of chitosan complex scaffolds in periodontal tissue engineering.

    [Key words]periodontal disease；periodontal tissue；periodontal tissue engineering；chitosan；scaffold；periodontal ligament cell

    牙周组织病变和缺损主要有生理性退行形变、病理性损害、废用性萎缩和遗传性牙槽骨缺失或狭窄，常表现为牙槽骨吸收、牙周溢脓、牙龈炎症，最终引起牙齿松动脱落；阻止牙周病变，重建因牙周疾病而丧失的支持组织(尤其牙骨质再生)备受业界的关注 ......