牙龈蛋白酶及其致病作用
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2012年12月1日
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[摘要]牙龈卟啉单胞菌是引起和加重牙周炎的重要致病菌,其分泌的牙龈蛋白酶是其主要的毒力因子之一。本文就牙龈卟啉单胞菌牙龈蛋白酶以及牙龈蛋白酶对细菌生长和黏附的影响、对组织的破坏作用、对宿主防御机制的作用等研究进展作一综述。
[关键词]牙龈卟啉单胞菌;牙龈蛋白酶;致病;作用
[中图分类号]Q 55[文献标志码]A[doi]10.3969/j.issn.1673-5749.2012.06.024
Gingipain and its pathogenicityFeng Qin1,2, Zhang Fengqiu1.(1. Dept. of Periodontics and Mucosa Disease, The Affiliated Beijing Stomatological Hospital of Capital Medical University, Beijing 100050, China; 2. Dept. of Stomatology, General Hospital of Beijing Jingmei Group, Beijing 102300, China)
[Abstract]Porphyromonas gingivalis(P.gingivalis)is recognized as the most important pathogen of periodontitis. Gingipain is thought to be one of the most important virulence factors of P ......
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