人参皂苷调控转化生长因子-β信号通路的作用机制(6)
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[36]Kang KA,Kim HS,Kim DH,et al.The role of a ginseng saponin metabolite as a DNA methyltransferase inhibitor in colorectal cancer cells[J].Int J Oncol,2013,43(1):228-236.
[37]Lim TG,Jeon AJ,Yoon JH,et al.20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol,a metabolite of ginsenoside Rb1,enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes[J].Int J Mol Med,2015,35(5):1388-1394.
[38]Bae J,Koo J,Kim S,et al.Ginsenoside Rp1 Exerts Anti-inflammatory Effects via Activation of Dendritic Cells and Regulatory T Cells[J].J Ginseng Res,2012,36(4):375-382.
[39]Barcellos-Hoff MH,Cucinotta FA.New tricks for an old fox:impact of TGFβ on the DNA damage response and genomic stability[J].Sci Signal,2014,7(341):re5.
[40]Santos JI,Teixeira AL,Dias F,et al.Restoring TGFβ1 pathway-related microRNAs:possible impact in metastatic prostate cancer development[J].Tumour Biol,2014,35(7):6245-6253.
[41]Heger J,Schulz R,Euler G.Molecular switches under TGFβ signalling during progression from cardiac hypertrophy to heart failure[J].Br J Pharmacol,2016,173(1):3-14.
[42]Sheng J,Chen W,Zhu HJ.The immune suppressive function of transforming growth factor-β(TGF-β)in human diseases[J].Growth Factors,2015,33(2):92-101., 百拇医药(郑思道 曹春 姚全)