Abstract Real-world study(RWS)has been developing fast in recent years under the guidance of clinical requirement and relevant policies， and has become a hot topic in the field of medical research.At present， the key contents of RWS， such as evidence level， bias control and value etc.， are still lack of in-depth discussion.The transparency of clinical research is an important guarantee for the standardization of research， the authenticity of results and the reliability of conclusions.This paper introduced the necessity of improving the transparency of RWS ......