杨星哲 李峰 毛萌 王若冲 张翼飞 徐一菲 李杰 宋丹丹 于佳慧

    摘要 疲劳已成为影响人们生命质量的重要因素。疲劳发病机制复杂，常规治疗缺乏有效方案，部分药物有成瘾性和不良反应。中药抗疲劳药物具有安全有效、多种功效协同作用的独特优势。肝脾肾功能失调是疲劳发生发展的重要病机，中药处方多以疏肝健脾补肾为主。现通过对疲劳的病机、处方用药、抗疲劳作用机制进行全面系统地总结，为中医药抗疲劳提供依据。

    关键词 作用机制;中药抗疲劳;肝脾肾功能失调;疏肝健脾补肾;神经免疫炎症;能量代谢;抗氧化活性

    Research Progress on Anti-fatigue Effect of Chinese Medicine

    YANG Xingzhe，LI Feng，MAO Meng，WANG Ruochong，ZHANG Yifei，XU Yifei，LI Jie，SONG Dandan，YU Jiahui

    (School of Traditional Chinese Medicine，Beijing University of Chinese Medicine，Beijing 100029，China)

    Abstract Fatigue has become an important factor affecting people′s quality of life.With high incidence，fatigue can be regarded as an independent disease and is a symptom of a variety of chronic diseases.Since many clinical drugs have common side effects，effective prevention and treatment of fatigue has become an urgent problem to be solved.As the pathogenesis of fatigue is complex，western medicines lack an effective and complete program and have the risk of addiction and side effects.Chinese medicines for resisting fatigue boast the unique advantages of safety ......