刘立伟 崔鑫 路宁宁 吕佳杰 范逸品 于大猛

    摘要 中药丸剂作为传统剂型具有便于储存、药效持久、服用方便的特点，临床上依据药性、毒性、病性、体质、疾病等特点制成丸剂，适用于慢性病后期的临床治疗。近年来呈现出多技术联用与新工艺探索的双模式，在辅料研究、提取工艺、质量评价、干燥、微生物灭活等方面取得了重要进展。现系统介绍近5年来中药丸剂的研究进展，以期为丸剂在生产中的应用提供参考。

    关键词 丸剂；辅料；干燥；提取工艺；质量评价；炼蜜；药辅合一；滴丸

    Research Progress on Traditional Chinese Medicine Pills

    LIU Liwei1，CUI Xin1，LU Ningning2，LYU Jiajie3，FAN Yipin1，YU Dameng1

    (1 Institute of Basic Research in Clinical Medicine，China Academy of Chinese Medical Sciences，Beijing 100091，China; 2 Hebei Agricultural University，Baoding 071001，China; 3 Nanjing University of Chinese Medicine，Nanjing 210023，China)

    Abstract As a traditional dosage form，traditional Chinese medicine(TCM) pills have the characteristics of easy storage，long-lasting efficacy，and convenient administration.TCM drugs are made into pills clinically based on the characteristics of drug properties，toxicity，disease nature，constitution，and disease，and they are suitable for the clinical treatment of late chronic diseases.The dual modes of the combination of multiple technologies and new process exploration have advanced in the research on excipients ......