郭建华 谷鸿彦

    [摘要] 自身免疫性肝病是一种特殊类型的肝脏疾病，其发病与患者免疫机制异常有关，临床多出现黄疸、发热、关节炎等症状，实验室检测可发现自身抗体，亦可合并其他系统自身免疫性疾病。治疗主要采用激素、硫唑嘌呤等免疫抑制剂。目前，随着我国医疗水平的逐步提高，对该疾病的认识和水平也有了长足的进步，本文就该疾病近年来的诊疗情况作一综述，以期能更深入地研究其发病机制及临床诊疗。

    [关键词] 自身免疫性肝病；发病机制；诊断；治疗

    [中图分类号] R575[文献标识码]A [文章编号]1673-7210(2011)11(c)-013-02

    The progress research of autoimmune liver disease

    GUO Jianhua, GU Hongyan

    The Hospital of Gaobeidian City, Hebei Province, Gaobeidian 074000, China

    [Abstract] Autoimmune liver disease (AILD) which is related to abnormality of immune system is a special type of the liver disease. The clinical appearance of AILD includes jaundice, fever, arthritis, and so on. Autoantibodies can be found in the patients by laboratory tests. The patients of AILD may also suffer from other autoimmune diseases. Hormones, azathioprine and other immunosuppressive agents are the main therapeutic drugs taken by these patients. Along with the development of medical service in our country, the understanding of ALID has gained great progress. To explore the pathogenesis and treatment of ALID further, this article reviews on the diagnosis and treatment of ALID in recent years. ......