韩芳

    [摘要] 目的 探讨心型脂肪酸结合蛋白(H-FABP)联合肌钙蛋白Ⅰ(cTnⅠ)对脑卒中继发性肺栓塞患者早期诊断及判断预后的价值。 方法 选取2011年1月～2014年4月北京市通州区潞河医院收治的150例脑卒中继发性肺栓塞患者(研究组)及单纯脑卒中患者150例(对照组)。检测并比较治疗前两组及研究组治疗前后H-FABP、cTnⅠ水平。 结果 治疗前研究组H-FABP[(9.52±2.67)μg/L]及cTnⅠ[(0.15±0.09)μg/L]水平明显高于对照组[(3.87±2.96)、(0.05±0.03)μg/L]，差异均有统计学意义(P < 0.05)；治疗后研究组患者血浆H-FABP、cTnⅠ水平分别为(5.51±1.97)、(0.08±0.03)μg/L，较治疗前明显降低，差异均有统计学意义(P < 0.05)。 结论 脑卒中继发性肺栓塞患者血浆H-FABP及cTnⅠ浓度明显升高，两指标联合有助于脑卒中继发性肺栓塞的早期诊断和短期预后情况的评估。

    [关键词] 肺栓塞；脑卒中；心型脂肪酸结合蛋白；肌钙蛋白I；诊断；预后

    [中图分类号] R542.22 [文献标识码] A [文章编号] 1673-7210(2014)09(c)-0039-03

    Association between heart-type fatty acid binding protein， cardiac troponin Ⅰ and stroke-associated pulmonary embolism

    HAN Fang1 ZHANG Weidong2 LIAO Xiaoling3 WANG Yongjun3

    1.Respiratory and Intensive Care Unit， Luhe Hospital of Tongzhou District in Beijing City， Beijing 101101， China； 2.Department of Neurology， Luhe Hospital of Tongzhou District in Beijing City， Beijing 101101， China； 3.Department of Neurology， Beijing Tiantan Hospital， Beijing 100050， China

    [Abstract] Objective To investigate the diagnosis and prognostic value of heart-type fatty acid binding protein combined cardiac troponin Ⅰ in stroke-associated pulmonary embolism patients. Methods 150 patients with stroke-associated pulmonary embolism (study group) and 150 patients of stroke without pulmonary embolism (control group) from January 2011 to April 2014 in Luhe Hospital of Tongzhou District in Beijing City were selected in this study. The H-FABP and cardiac troponin Ⅰ of patients in two groups before treatment and those of the study group after treatment were detected and compared. Results The levels of plasma H-FABP and cardiac troponin Ⅰ of patients before treatment in study group [(9.52±2.67) ......