颜晶晶等

    [摘要] 肺动脉高压(PH)是慢性阻塞性肺疾病(COPD)的一种常见合并症，它被广泛认为是影响COPD患者临床症状、发病率、病死率及预后的独立因素。这一观点激励人们对COPD相关PH的发病机制进行深入研究，为新的治疗方案的研发提供理论依据。同时完善相关实验室及临床检查对该病的及早发现、诊断及治疗起到了积极的意义。只有对COPD患者进行详细的评估，筛选出PH人群，才能制订出明确的治疗方案，从而达到更好的临床治疗效果。本研究就COPD相关PH的发病机制、临床特点及相关诊断方法作一综述。

    [关键词] 肺动脉高压；慢性阻塞性肺疾病；机制；诊断

    [中图分类号] R563.9 [文献标识码] A [文章编号] 1673-7210(2014)11(a)-0163-04

    Progress in diagnosis of pulmonary hypertension associated with chronic obstructive pulmonary disease

    YAN Jingjing ZHAO Dongfang LIU Zheng

    Department of Respiratory， Petroleum Clinical Medical College of Hebei Medical University， Hebei Province， Langfang 065000， China

    [Abstract] Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease. It is widely recognized as an independent factor to the clinical manifestations， morbidity， mortality and prognosis of the COPD disease process. This recognition stimulates further research on the pathogenesis of PH associated with COPD as the basis for exploring new therapeutic strategies. Meanwhile， the related laboratory and clinical examinations are necessary for detection ......