黄通等

    [摘要] 目的 探讨N末端脑钠素原(NT-proBNP)水平与冠心病患者危险分层及全球急性冠状动脉事件注册(GRACE)评分的相关性。 方法 回顾性分析2013年1月～2014年4月在深圳市南山区慢性病防治院行冠状动脉造影检查的冠心病患者231例的临床资料，根据患者的冠状动脉狭窄情况以及临床症状和体征分为对照组(57例)、稳定型心绞痛组(95例)、急性冠脉综合征组(79例)。冠心病危险分层：GRACE评分140分为高危(38例)。所有患者检测NT-proBNP水平，分析NT-proBNP与危险分层以及GRACE评分的关系。采用统计学软件InStat 3.06进行数据的分析和处理。 结果 对照组、稳定型心绞痛组和急性冠脉综合征组的NT-proBNP水平分别为(336.1±117.9)、(814.5±279.4)、(3174.2±416.8)pg/mL；急性冠脉综合征组显著高于对照组和稳定型心绞痛组，稳定型心绞痛组显著高于对照组(均P 140 as high risk (38 cases). NT-proBNP levels of all patients were detected， and correlation of NT-proBNP level with risk stratification and GRACE score in patients with coronary heart disease was analyzed. The data were analyzed by the statistical software InStat 3.06. Results NT-proBNP level of control group， stable angina group and acute coronary syndrome group was (336.1±117.9)， (814.5±279.4)， (3174.2±416.8) pg/mL respectively. NT-proBNP level of acute coronary syndrome group was apparently higher than that of control group and stable angina group respectively ......