类风湿关节炎的诊断及其药物治疗研究进展
许相洋+张文州[摘要] 类风湿关节炎(RA)是一种慢性的炎性难治性自身免疫性关节病,其发病机制尚未清楚,可能与环境、遗传、免疫因素等息息相关,目前仍无法完全治愈,仍以控制为主。本文综述了RA临床常见的诊断方法和治疗RA的化学类药物(改变病情抗风湿药、糖皮质激素、非甾体抗炎药)、中药类药物(单味中药、复方中药等)以及生物类药物,以期为今后RA的诊疗提供参考和依据。
[关键词] 类风湿关节炎;临床诊断;化学类药物;中药类药物;生物类药物
[中图分类号] R593.22 [文献标识码] A [文章编号] 1674-4721(2016)10(c)-0056-04
[Abstract] Rheumatoid arthritis (RA) is a kind of chronic refractory autoimmune inflammatory disease. Its pathogenesis is still unclear. The pathogenesis may closely related to the environmental, genetic and immune factors. RA cannot cure completely and control-oriented at present. This paper reviewed the clinical diagnosis of RA and the durgs of chemical (NSAIDs, GCS, DEMARDs), traditional Chinese medicine (single Chinese herb, compound Chinese medicine etc) and biological, which hope to provide reference and basis for RA medicine in the future.
[Key words] Rheumatoid arthritis; Clinical diagnosis; Chemical durgs; Traditional Chinese medicine; Biological durgs
类风湿关节炎(rheumatoid arthritis,RA)的病变主要有滑膜炎、类风湿结节、血管炎等,临床常见症状主要有晨僵、关节肿胀和关节疼痛,后期可能导致关节严重变形,甚至出现畸形、脱位等症状。本文主要通过综合论述近年来国内外对RA的检查手段和治疗药物的最新进展 ......
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