孙元隆 王肖龙 阮小芬

    [摘要] 自发性冠状动脉夹层是指冠状动脉内膜自发撕裂或冠状动脉壁内滋养血管出血形成血管夹层，临床较为少见，主要表现为急性冠脉综合征和心源性猝死，其发生与冠状动脉粥样硬化、激素水平变化、肌纤维发育不良、全身性炎性疾病和结缔组织缺陷等因素相关，可累计单支、多支冠状动脉，可通过冠状动脉造影、血管内成像技术等明确诊断。

    [关键词] 自发性冠状动脉夹层；病因；病理生理；诊断

    [中图分类号] R543.3 [文献标识码] A [文章编号] 1673-7210(2016)12(c)-0067-04

    [Abstract] Spontaneous coronary artery dissection is spontaneous coronary artery intimal tear or bleeding in the nutrient vessel with relatively low incidence. The main manifestations of spontaneous coronary artery dissection are acute coronary syndrome and sudden cardiac death caused by coronary atherosclerosis， hormone level change， fibromuscular dysplasia， systemic inflammatory disease， connective tissue disorders and other related factors， involving single coronary artery or multi-coronary arteries. It can be diagnosed by coronary angiography， intravascular unltrasound， etc.

    [Key words] Spontaneous coronary artery dissection； Etiologies； Pathophysiology； Diagnosis

    自發性冠状动脉夹层(spontaneous coronary artery dissection，SCAD)是指未经人为干预，冠状动脉内膜自发撕裂或动脉壁内滋养血管出血形成血管夹层，影响血流或者造成血管闭塞，主要表现为急性冠脉综合征(acute coronary syndrome ......