吴瑞++++++董治燕++++++李海军

    [摘要] 目的 探討鼠神经生长因子联合依达拉奉用于治疗脑出血的临床效果及对神经功能的影响。 方法 选择2014年1月～2016年10月延安大学附属医院收治的70例脑出血患者为研究对象，根据治疗方法的不同将其分为对照组和观察组，每组各35例。对照组患者在常规治疗的基础上给予依达拉奉注射液治疗，观察组在对照组治疗的基础上给予肌内注射鼠神经生长因子制剂。治疗前后，采用神经功能缺损评分(NIHSS)量表评估两组患者的神经功能缺损程度；采用酶联免疫吸附法测定血清神经元特异性烯醇化酶(NSE)、S100B蛋白水平及血清超敏C反应蛋白(hs-CRP)、白细胞介素8(IL-8)和肿瘤坏死因子α(TNF-α)水平。采用脑卒中影响量表(SIS)评价患者治疗后的生活质量。 结果 两组有效率(97.14%比74.29%)比较差异有统计学意义(P 0.05)。 结论 鼠神经生长因子联合依达拉奉治疗脑出血患者效果显著，可明显降低患者炎症因子水平，改善神经功能，提高患者的生活质量，值得在临床上推广应用。

    [关键词] 鼠神经生长因子；依达拉奉；脑出血；神经功能

    [中图分类号] R743.3 [文献标识码] A [文章编号] 1673-7210(2017)02(b)-0145-04

    [Abstract] Objective To study the clinical effect of mouse nerve growth factor combined with Edaravone in the treatment of cerebral hemorrhage and the effect on neural function. Methods Seventy cases of patients with cerebral hemorrhage admitted to the Affiliated Hospital of Yan'an University from January 2014 to October 2016 were selected as the research objects， according to the treatment methods， they were divided into control group and observation group， with 35 cases in each group. The two groups were given the routine therapy ......