张京+卢新+刘晓红+宜小如

    [摘要] 目的 分析孕妇不规则抗体阳性结果，了解不规则抗体的临床意义。 方法 采用戴安娜微柱凝胶抗人球蛋白检测卡，对2015年10月～2016年9月于北京市海淀区妇幼保健院建卡就诊的14 287例孕妇血清中不规则抗体进行检测，对阳性结果者进一步鉴定其特性。 结果 14 287例孕妇中检出不规则抗体阳性63例，21例为RH阴性孕妇，在产前注射过免疫球蛋白，实际不规则抗体阳性孕妇42例，阳性率为0.294%，14 287例孕妇中9246例为多次妊娠的孕妇。不规则抗体的类型有抗D 2例，抗E 8例，抗C 7例，抗CD 1例，抗Ce 6例，抗cE 6例，抗M 4例，抗S 1例，抗Fyb 4例；抗Lea 3例。 结论 围生期孕妇产前不规则抗体筛检具有临床应用价值，应将其列入产前血清学检查常规项目。

    [关键词] 不规则抗体；围生期；免疫球蛋白；临床意义

    [中图分类号] R714 [文献标识码] A [文章编号] 1673-7210(2017)03(b)-0096-03

    Result analysis and clinical significance of irregular antibody about 14 287 pregnancies

    ZHANG Jing LU Xin LIU Xiaohong YI Xiaoru

    Department of Clinical Laboratory， Maternal and Child Health Care Hospital of Haidian District， Beijing 100081， China

    [Abstract] Objective To analyze positive results of irregular antibody about pregnancy， and to understand clinical significance of irregular antibody. Methods Diana micro column gel anti globulin test card was used in irregular antibody. Irregular antibodies of 14 287 pregnancies from October 2015 to September 2016 were detected in Maternal and Child Health Care Hospital of Haidian District ......