李双++李艳波

    [摘要] 随着经济发展和生活水平的提高，人们生活方式、饮食习惯发生了很大改变，导致高尿酸血症(hyperuricemia，HUA)和糖尿病(diabetes mellitus，DM)的发生率越来越高。研究表明，尿酸(uric acid，UA)与2型糖尿病(type 2 diabetes mellitus，T2DM)的关系仍不确切，高尿酸血症对2型糖尿病的发生起一定保護作用，但也可促进其发生和进展。高尿酸血症可促进糖尿病大血管病变、微血管病变、神经病变、糖尿病足等的发生发展，但尿酸过低同样促进糖尿病神经病变的进展。因此尿酸水平控制在合理范围，以预防糖尿病及其慢性并发症发生，应引起重视。

    [关键词] 尿酸；2型糖尿病；糖尿病慢性并发症

    [中图分类号] R587.1 [文献标识码] A [文章编号] 1673-7210(2017)04(b)-026-04

    [Abstract] With the improvement of economic development and living standards， people living style and dietary habits have changed greatly so that the incidences of hyperuricemia and diabetes mellitus are getting higher and higher. Research shows that the relationship between uric acid and type 2 diabetes mellitus is still not precise. Hyperuricemia has a protective effect on the occurrence of type 2 diabetes， and also can promote the occurrence and progression. Hyperuricemia can promote diabetic vascular lesions， microvascular lesion， neuropathy and diabetic foot development， and low uric acid can also promote the progress of diabetic neuropathy. Therefore reasonable range of uric acid in the prevention of diabetes and diabetic chronic complications should be paied more attention. ......