苏冬云

    [摘要] 目的 探討2型糖尿病患者静息心率(RHR)预测早期糖尿病肾病的价值。 方法 选择2013年1月～2016年12月就诊于扬州大学附属淮安市妇幼保健院内科门诊的120例2型糖尿病患者作为研究对象，按RHR水平将入选的患者分为三组：RHR1组(RHR≤70次/min)、RHR2组(70次/min 0，P < 0.05)；RHR与估算肾小球滤过率和立卧位心率差均呈负相关(r < 0，P < 0.05)。RHR预测早期肾脏损伤ROC曲线下面积为0.881(0.806～0.956)，差异有统计学意义(P < 0.05)。其诊断界值为78次/min，敏感度为76.7%，特异度为91.1%，阳性预测值为71.8%，阴性预测值为92.1%。 结论 2型糖尿病患者的RHR与早期肾损伤相关，RHR可作为2型糖尿病发生早期糖尿病肾病的预警指标。

    [关键词] 2型糖尿病；静息心率；肾损伤；早期糖尿病肾病

    [中图分类号] R587.2 [文献标识码] A [文章编号] 1673-7210(2018)02(b)-0058-04

    [Abstract] Objective To investigate the value of the resting heart rate (RHR) in predicting early diabetic nephropathy (EDN) in patients with type 2 diabetes mellitus. Methods One hundred and twenty patients with type 2 diabetes mellitus treated in department of internal medicine of Huai'an Maternity and Child Healthcare Hospital affiliated to Yangzhou university from January 2013 to December 2016 were selected as research objects. The enrolled patients were devided into RHR1 group (RHR≤70 times/min)， RHR2 group (70 times/min 0， P < 0.05). The area under the ROC curve of early renal injury predicted by RHR was 0.881 (0.806-0.956) ......