王增夏 王贺 邱承杰 司春婴 赵亚楠 关怀敏 解金红

    [摘要] 心房颤动(简称房颤)是临床上最常见的心律失常之一，目前，其发病机制尚未完全清楚，本篇主要从房颤的电生理机制(局灶触发机制、多发子波折返等)和病理生理机制(电重构、收缩重构、结构重构等)出发对房颤的可能发病机制进行综述，以期为房颤的预防和治疗提供依据或方向。

    [关键词] 心房颤动；发病机制；电重构；结构重构；炎症；氧化应激

    [中图分类号] R541.75 [文献标识码] A [文章编号] 1673-7210(2018)05(c)-0026-04

    Research progress on pathogenesis of atrial fibrillation

    WANG Zengxia1 WANG He2 QIU Chengjie2 SI Chunying2 ZHAO Ya′nan1 GUAN Huaimin3 XIE Jinhong2

    1.The First Shool Clinical Medicine， He′nan University of Chinese Medicine， He′nan Province， Zhengzhou 450000， China； 2.the Third Ward of Cardiovascular Medicine， the First Affiliated Hospital of He′nan University of Chinese Medicine， He′nan Province， Zhengzhou 450000， China； 3.Heart Center， the First Affiliated Hospital of He′nan University of Chinese Medicine， He′nan Province， Zhengzhou 450000， China

    [Abstract] Atrial fibrillation (AF) is the most common arrhythmia diagnosed in clinical practice. Now， precise mechanisms that lead to the onset and persistence of AF have not completely been elucidated. This paper mainly from the electrophysiological mechanisms of atrial fibrillation (including focal triggering mechanism ......