肖玲 邹丽颖

    [摘要] 单核细胞增多性李斯特氏菌属于李斯特氏菌属，为人畜共患的致病菌，人类主要是通过食用被污染食品而感染，感染后可导致李斯特菌病。该病原菌可产生一种溶血性外毒素，对人类有很强的致病性，常见于免疫功能低下的者，如妊娠、老年人、免疫缺陷者以及胎儿、新生儿(通过母婴垂直传播或少数者通过阴道分娩时感染)等。人体感染后可引起菌血症、败血症、脑膜炎及流产等症状，因其症状不典型，导致诊断困难。李斯特菌病有较高的死亡率。本文旨在阐述妊娠期单核细胞增多性李斯特菌感染及对母儿的影响，以改善妊娠结局。

    [关键词] 菌血症；单核细胞增多性李斯特氏菌；李斯特菌病；流行病学；妊娠

    [中图分类号] R714 [文献标识码] A [文章编号] 1673-7210(2018)05(c)-0030-04

    Listeria Monocytogenes infection in pregnancy and its impact on mother and infant

    XIAO Ling1 ZOU Liying2▲

    1.Department of Obstetrics， the First Maternal and Child Health Hospital of Dongchen District， Beijing 100007， China； 2.Department of Obstetrics， Beijing Obstetrics and Gynaecology Hospital， Capital Medical University， Beijing 100026，China

    [Abstract] Listeriosis is an anthropozoonosis caused by Listeria monocytogenes (L. monocytogenes). It is acquired by humans primarily through consumption of contaminated food. Listeria monocytogenes has strong pathogenicity to human through produced the hemolytictoxin， especially high risk patients such as pregnant women， elderly people， immuno compressed people ......