何景良 梁志会 李亮

    [摘要] 目的 探討介入治疗急性下肢动脉栓塞的临床效果。 方法 选择2016年6月～2017年6月解放军白求恩国际和平医院诊治的急性下肢动脉栓塞60例，按照治疗方式的不同分为两组，其中对照组30例行大腔导管抽吸血栓治疗，实验组30例行大腔导管抽吸血栓+置管溶栓治疗。比较两组治疗效果和两组患者凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)及D-二聚体(D-D)水平，观察两组患者的复发率及截肢率。 结果 治疗后，实验组总有效率明显高于对照组，差异有统计学意义(P 0.05)。 结论 临床中对急性下肢动脉栓塞患者应用大腔导管抽吸血栓+置管溶栓治疗效果显著，且并发症少，临床效果优于单纯应用大腔导管抽吸血栓治疗，可进行推广。

    [关键词] 急性下肢动脉栓塞；介入治疗；大腔导管抽吸血栓；置管溶栓

    [中图分类号] R654.4 [文献标识码] A [文章编号] 1673-7210(2018)09(a)-0071-04

    [Abstract] Objective To investigate the clinical efficacy of interventional therapy for acute lower extremity arterial embolism. Methods From June 2016 to June 2017， in PLA Bethune International Peace Hospital， 60 patients with acute arterial embolism of lower extremity were selected， according to the treatment methods， they were divided into two groups， 30 cases in the control group were treated with large cavity catheter sucking thrombus， and 30 cases in the experiment group were treated with large cavity catheter sucking thrombolytic thrombolysis plus catheter thrombolytic therapy. The treatment effect， prothrombin time (PT)， activated partial thromboplastin time (APTT) ......