王怀湘 李建明

    [摘要] 目的 評价微波凝固辅助强脉冲光(IPL)治疗玫瑰痤疮的效果及安全性。 方法 选取2014年2月～2017年1月在火箭军总医院礼士路门诊部皮肤科就诊的64例玫瑰痤疮患者，按随机数字表法将其分为观察组和对照组，每组32例。观察组先给予IPL治疗，再用微波凝固扩张的毛细血管，对照组仅给予IPL治疗。观察并比较两组患者临床效果、副作用及治疗前后症状积分、皮肤病的生活质量指数量表(DLQI)评分。 结果 观察组在治疗后3、6、9周总有效率均明显高于同期对照组(P 0.05)。两组皮损总评分和DLQI评分的组间效应、时间效应及交互作用整体差异均有统计学意义(P 0.05)。 结论 微波凝固技术辅助IPL治疗鼻部及鼻周以毛细血管扩张为主的玫瑰痤疮效果确切，安全可靠，患者恢复时间短，生活质量得到明显改善，值得临床推广使用。

    [关键词] 强脉冲光；微波；玫瑰痤疮；临床疗效

    [中图分类号] R758.64 [文献标识码] A [文章编号] 1673-7210(2018)09(b)-0113-04

    [Abstract] Objective To evaluate the efficacy and safety of microwave coagulation assisted intense pulse light (IPL) in the treatment of rosacea. Methods From February 2014 to January 2017， 64 patients with rosacea in the Department of Dermatology in Lishilu Outpatient， General Hospital of the PLA Rocket Force were divided into observation group and control group according to random number table method， with 32 cases in each group. The observation group was treated with IPL and microwave to coagulate the dilated capillaries， while the control group was treated with IPL only. The clinical effects， side effects ......