裴悦 莫秀梅 曾剑波 薛素琴 晏烽根 陈达灿 刘俊峰 李红毅

    [摘要] 目的 分析探讨当代中医对特应性皮炎(AD)的辨证治疗的经验。 方法 基于关联规则算法和复杂系统熵聚类，通过检索2017年1月1日～2018年3月1日发表于中国知网、万方、维普、中国生物医学文献数据库中中医药治疗AD的文献，建立包含辨证分型、内服及外用中药的数据库，利用中医传承辅助平台V2.5进行数据分析。 结果 内服中药四气分布主要为温、寒、平、凉，药物的五味分布主要为甘、苦、辛、淡，药物归经多集中于脾肺。内服中药以茯苓、甘草、生地、白鲜皮、当归等15味药频次居多，外用中药以黄柏、苦参、白鲜皮、马齿苋、地肤子等10味中药频数最高。 结论 AD辨证分型多集中于脾虚证，兼夹有湿邪、血燥。中药内服方以“健脾益气祛湿，祛风养血润燥”为主要治法，外用方以“清热燥湿，解毒止痒”为则;处方用药多从脾论治，可为中医临床辨证用药提供参考。

    [关键词] 特应性皮炎;辨证用药;组方规律;关联规则;聚类算法

    [中图分类号] R275? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-7210(2019)01(c)-0124-04

    [Abstract] Objective To analyze and discuss the experience of symptom differentiation of atopic dermatitis (AD) and its treatment with modern Chinese medicine. Methods Based on the association rule algorithm and entropy clustering of complex system， Chinese medicine literature database on the treatment of atopic dermatitis in CNKI， Wanfang， VIP， China biomedical literature database from January 1st 2017 to March 1st 2018 was retrieved. And a database containing syndrome differentiation， Chinese medicine for internal and external use was established. TCMISS V2.5 was used to analyze the data. Results The distribution of four Qi of traditional Chinese medicine was mainly warm ......