姜海龙 毛存南 陈谦

    [摘要] 目的 探讨在3.0T MRI联合低浓度对比剂增强磁共振血管成像(CE-MRA)和动态磁敏感灌注成像(DSC-PWI)在急性缺血性脑卒中的应用价值。 方法 收集南京市第一医院2017年10月～2018年3月急性脑卒中患者30例，所有患者均接受低浓度对比剂CE-MRA和DSC-PWI成像，并于24 h内接受数字减影血管造影(DSA)检查。CE-MRA和DSC-PWI均使用半剂量对比剂浓度(0.05 mmol/kg)。通过与DSA对照，评估CE-MRA对血管狭窄诊断的准确性。CE-MRA诊断血管狭窄及DSC-PWI诊断不匹配区的观察者间一致性检验使用Kappa分析。结果 CE-MRA对头颈动脉低级别(50%)狭窄诊断的敏感性、特异性、阳性预测值、阴性预测值分别为82.4%、100%、100%、93.8%及100%、82.4%、93.8%、100%。CE-MRA诊断动脉狭窄及DSC-PWI诊断不匹配区观察者之间一致性均好(κ = 0.87、0.86)。 结论 3.0T MRI联合低浓度对比剂CE-MRA和DSC-PWI是一种可行的急性缺血性脑卒中MRI扫描方案。

    [关键词] 急性缺血性脑卒中；磁共振成像；钆对比剂；头颈动脉

    [中图分类号] R445.2 [文献标识码] A [文章编号] 1673-7210(2019)04(a)-0150-04

    Application value of low-dose contrast-enhanced MR angiography and perfusion imaging at 3.0T in patients with acute ischemic stroke

    JIANG Hailong MAO Cunnan CHEN Qian CHEN Guozhong YIN Xindao

    Department of Radiology， Nanjing Hospital Affiliated to Nanjing Medical University， Nanjing First Hospital， Jiangsu Province， Nanjing 210006， China

    [Abstract] Objective To explore application value of low-dose contrast-enhanced MRA (CE-MRA) and dynamic susceptibility contrast perfusion imaging (DSC-PWI) at 3.0T in patients with acute ischemic stroke. Methods Thirty patients with acute ischemic stroke in Nanjing First Hospital from October 2017 to March 2018 were enrolled. All the patients underwent low-dose CE-MRA and DSC-PWI examination ......