徐雨 丁佑铭 赵凯亮

    [摘要] 脾动脉盗血综合征是指门脉高压症合并脾亢患者，在发生脾动脉增粗和血流加速的病理基础上，脾动脉与肝动脉竞争腹腔干血流，导致肝动脉灌注减少，从而引起以肝细胞与胆管细胞缺血、缺氧性损伤为特点的综合征，也是肝移植术后导致移植物功能丧失以及受体死亡的原因之一。本文将从肝移植术后脾动脉盗血综合征发生的原理、诊断及防治等方面作一综述。

    [关键词] 肝移植；脾动脉盗血综合征；并发症；预防

    [中图分类号] R657.3 [文献标识码] A [文章编号] 1673-7210(2019)04(c)-0027-04

    [Abstract] Splenic artery steal syndrome (SASS) is a syndrome characterized by ischemia and hypoxic injury of hepatocytes and cholangiocytes caused by competition between splenic artery and hepatic artery for celiac trunk blood flow in patients with portal hypertension and hypersplenism. It is also one of the causes of graft dysfunction and death of recipients after liver transplantation. This article reviews the principles， diagnosis， prevention and treatment of SASS after liver transplantation.

    [Key words] Liver transplantation； Splenic artery steal syndrome； Complications； Prevention

    肝移植术(liver transplantation)术后并发症主要包括血管并发症、胆道并发症[1]以及排斥反应等。血管并发症是肝移植术后最危险的并发症之一[2]。其中，与动脉相关的术后并发症是导致肝移植术后移植物功能丧失的重要因素[3]。脾动脉盗血综合征(splenic artery steal syndrome，SASS)的产生是因为肝动脉内的血流过多地分流至脾动脉，导致肝脏低灌注，而引起一系列相关的综合征[4] ......