张金玲 肖喜刚 袁彪

    [摘要] 目的 探討低浓度对比剂在低kV扫描模式下兔肝脏双期CT增强成像的可行性。 方法 选取家兔14只(3.5～4.0月龄，体重2.0～2.5 kg)，并根据扫描模式将其分为A、B、C组，其管电压分别为120、100、80 kV，对比剂浓度A组为350 mgI/mL，B、C组为270 mgI/mL，所有研究对象均按A～C组的扫描条件进行肝脏CT双期增强扫描，分别测量肝门水平门静脉、腹主动脉、腹壁肌肉及肝实质的CT值和噪声，计算对比噪声比(CNR)及信噪比(SNR)。由2名有经验的放射科医生对所有图像进行主观评分。 结果 三组有效辐射剂量比较，差异有统计学意义(P 0.05)；而三组肝实质SNR、噪声比较，差异有统计学意义(P 0.05)；三组门静脉及腹主动脉CT值比较，差异有统计学意义(P 0.05)，但其中A组对比度、噪声评价高于C组，差异有统计学意义(P 0.05)。 结论 低浓度对比剂结合低kV扫描可以降低有效辐射剂量，升高血管CT值，结合ASIR重建技术，还能提高图像质量，满足诊断需求，为临床肝脏增强扫描提供理论依据。

    [关键词] 低浓度对比剂；肝脏；体层摄影术；家兔

    [中图分类号] R816.5 [文献标识码] A [文章编号] 1673-7210(2019)05(a)-0147-05

    [Abstract] Objective To investigate the feasibility of dual-phase CT enhanced imaging of rabbit liver in low-kV scan mode with low concentration contrast agent. Methods Fourteen rabbits (3.5-4.0 months age， weighing 2.0-2.5 kg) were selected and divided into groups A， B and C according to the scanning mode， and the tube voltages were 120， 100 and 80 kV， respectively， the contrast medium concentration was 350 mgI/mL in group A and 270 mgI/mL in group B and C. All subjects underwent dual-phase enhanced CT scanning according to the scanning conditions of group A-C. The CT value and noise of portal vein ......