吴素琴 史楠 李婷

    [摘要] 目的 研究坤草芪蓮汤治疗消渴病并发尿微量蛋白的临床效果。 方法 选取2017年6月～2018年12月山东省菏泽市中医医院收治的消渴病并发尿微量蛋白患者88例，按随机数字表法将其分为对照1组(28例)、对照2组(30例)和研究组(30例)。对照1组给予马来酸依那普利片治疗，对照2组在对照1组的基础上联用六味地黄汤治疗，研究组在对照1组的基础上联用坤草芪莲汤。比较三组临床疗效、中医主要症状积分、血肌酐(Scr)、血清胱抑素C(CysC)、内生肌酐清除率(Ccr)、24 h尿蛋白定量、24 h尿微蛋白排泄量及不良反应情况。 结果 研究组总有效率高于对照1组和对照2组，对照2组高于对照1组(P 0.05)。 结论 坤草芪莲汤治疗消渴病并发尿微量蛋白患者效果确切，安全性较高，可为临床治疗提供参考。

    [关键词] 消渴病;尿微量蛋白;坤草芪莲汤;效果

    [中图分类号] R587.1? [文献标识码] A? [文章编号] 1673-7210(2020)01(c)-0143-04

    Clinical effect of Kuncao Qilian Decoction in the treatment of consumptive thirst complicated with urine microprotein

    WU Suqin? SHI Nan? LI Ting

    Department of Endocrinology， Heze Traditional Chinese Medicine Hospital， Shandong Province， Heze? 274000， China

    [Abstract] Objective To study clinical effect of Kuncao Qilian Decoction in the treatment of consumptive thirst complicated with urine microprotein. Methods Eighty-eight cases of consumptive thirst complicated with urine microprotein who were treated in Heze Traditional Chinese Medicine Hospital from June 2017 to December 2018 were selected. They were divided into control group 1 (28 cases) ......