韩玉梅 田风胜 白海龙

    [摘要] 糖尿病肾病是糖尿病最常见的微血管并发症之一。随着病程的进展，加重了营养物质维生素D的丢失，同时对维生素D的羟化不足，共同导致骨质疏松的发生，属于中医肾主骨生髓理论。维生素D是一种类固醇激素，其缺乏不仅导致骨质疏松，而且参与糖尿病肾病发生、发展。骨质疏松给家庭、社会带来重担，引起越来越多人的重视。

    [关键词] 糖尿病肾病;维生素D;骨质疏松

    [中图分类号] R587.1 ? ? ? ? ?[文献标识码] A ? ? ? ? ?[文章编号] 1673-7210(2020)07(a)-0043-04

    [Abstract] Diabetic nephropathy is one of the most common microvascular complications of diabetes. With the progress of the course of the disease， the loss of vitamin D increases， and the lack of hydroxylation of vitamin D lead to the occurrence of osteoporosis， which belongs to the kidney main bone marrow theory of traditional Chinese medicine. Vitamin D is a steroid hormone， and its deficiency is not only linked to osteoporosis， but also to the development of diabetic kidney disease. Osteoporosis brings heavy burden to family and society， which attracts more and more people′s attention.

    [Key words] Diabetic nephropathy; Vitamin D; Osteoporosis

    2型糖尿病起病隱匿，多数患者一经确诊已合并视网膜、肾脏、周围神经多种慢性微血管并发症。近几年，研究发现，2型糖尿病患者的骨质疏松症明显高于普通人，预计到2025年，其发生率可增加30%～50%[1]。糖尿病合并肾脏病时，钙磷代谢、25羟维生素D、骨密度等均发生了相应变化。维生素D与2型糖尿病肾病的发病、进展密不可分 ......