徐明 唐澍 刘琦

    [摘要] 目的 探討槐耳颗粒联合紫杉醇和奥沙利铂治疗晚期胃癌的临床效果。 方法 选择2017年1月～2019年1月于湖南省郴州市第一人民医院进行治疗的晚期胃癌患者100例作为研究对象，通过随机数字表法分为观察组(50例)和对照组(50例)。对照组使用紫杉醇和奥沙利铂治疗，观察组在对照组基础上加用槐耳颗粒进行治疗。比较两组患者临床疗效、血清癌胚抗原(CEA)、糖链抗原724(CA724)、糖链抗原199(CA199)、T淋巴细胞亚群、生活质量及不良反应。 结果 观察组总有效率高于对照组，差异有统计学意义(P 0.05)。 结论 晚期胃癌患者使用槐耳颗粒联合紫杉醇和奥沙利铂效果显著，可有效改善患者血清肿瘤标志物水平和生活质量。

    [关键词] 槐耳颗粒;紫杉醇;奥沙利铂;晚期胃癌

    [中图分类号] R735.2 ? ? ? ? ?[文献标识码] A ? ? ? ? ?[文章编号] 1673-7210(2020)07(a)-0097-04

    [Abstract] Objective To explore the clinical effect of Huaier Granule combined with Taxol and Oxaliplatin in the treatment of advanced gastric cancer. Methods A total of 100 patients with advanced gastric cancer who were treated in Chenzhou NO.1 People′s Hospital from January 2017 to January 2019 were selected as the research object， while they were divided into observation group (50 cases) and control group (50 cases) by random number table method. The control group was treated with Taxol and Oxaliplatin ......