韦玉华 谢成琴 葛北海

    [摘要] 目的 探究腎素-血管紧张素Ⅱ-醛固酮及心率变异性水平在高血压合并抑郁症患者中的变化。 方法 选取2018年5月～2019年6月广西壮族自治区脑科医院(以下简称“我院”)51例高血压患者，依据有无合并抑郁症分为高血压合并抑郁症组(21例)及单纯高血压组(30例)，另选我院同期健康人群30名作为对照组。检测分析三组人群血浆肾素、血管紧张素Ⅱ、醛固酮浓度及心率变异性指标[正常相邻RR间期标准差(SDNN)、相邻RR间期差值均方的平方根(RMSSD)、相邻RR间期>50 ms的百分比(PNN50)]。 结果 高血压合并抑郁症组及单纯高血压组的肾素、血管紧张素Ⅱ、醛固酮水平高于对照组，且高血压合并抑郁症组肾素、醛固酮水平高于单纯高血压组，差异有统计学意义(P 50 ms (PNN50)] in three groups were detected and analyzed. Results The levels of renin， angiotensin Ⅱ and aldosterone in hypertension combined with depression group and simple hypertension group were higher than those in the control group， while the levels of renin， aldosterone in hypertension combined with depression group were higher than those in simple hypertension group， and the differences were statistically significant (P 50 ms的百分比(PNN50) ......