孕妇血清风疹病毒抗体IgM检测的临床意义(1)
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【摘要】 目的 探讨孕妇血清风疹病毒IgM抗体检测的临床价值。方法 采用酶联免疫吸附法(ELISA)检测230例孕妇血清中的风疹病毒特异性抗体IgM。结果 230例中IgM阳性20例，阳性率为8.70%；多次妊娠者IgM阳性率(25.93%)明显高于初次妊娠者(6.40%)(χ2=11.43,P<0.05);IgM阳性孕妇的早期流产率为31.58%(6/19)，而IgM阴性孕妇的早期流产率为8.53%(11/129)，两者比较差异有统计学意义(P<0.05) 。结论 孕妇血清风疹病毒IgM抗体的测定有助于预测妊娠结局、降低先天性风疹综合征患儿的出现率。
【关键词】妊娠；风疹病毒；酶联免疫吸附试验；IgM
The clinical value of detecting RV-IgM antibody in sera of pregnant women
XIA Xiu-ling.Child Health Care Hospital,Linqing City,Shandong Province 252600,China
【Abstract】 ObjectiveTo investigate the clinical value of detecting RV-IgM antibody in sera of pregnant women. Methods Enzyme-linked immunosorbent assay(ELISA) was used to detect RV-IgM specific antibody in sera of pregnant women. ResultsThe positive rate of RV-IgM of the 230 pregnant women were 8.70%(20/230);The positive rate of RV-IgM in multigravida (25.93%) was markedly higher than primigravid women(6.40%)(χ2=11.43,P<0.05); The early abortion rate of IgM-positive pregnant women was 31.58%(6/19), whereas IgM-negative pregnant women was 8.53%(11/129)(χ2=8.65,P<0.05). Conclusionthe detection of RV-IgM specific antibody in sera of pregnant women will help to predict pregnancy outcome, and reduce the frequency of congenital rubella syndrome infant ......
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