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蕲蛇酶与依达拉奉联合应用治疗急性脑梗死
http://www.100md.com 2008年12月25日 《中国实用医药》 2008年第36期
蕲蛇酶与依达拉奉联合应用治疗急性脑梗死

     【摘要】 目的 研究蕲蛇酶与自由基清除剂依达拉奉联合治疗急性脑梗死的疗效。方法 初次急性脑梗死患者81例,随机分为单独使用蕲蛇酶治疗组41例和蕲蛇酶联合依达拉奉治疗组40例。对两组的疗效进行对照研究。结果 联合治疗组的疗效优于单独使用蕲蛇酶组(P<0.05)。治疗后30 d联合治疗组NIHSS评分较单独使用蕲蛇酶治疗组显著下降(P<0.05)。结论 急性脑梗死治疗时蕲蛇酶与依达拉奉联合能够更有效地减少神经功能缺损程度。【关键词】急性脑梗死;蕲蛇酶;依达拉奉

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    Combined intravenous acutase and edaravone for acute cerebral infarction

    YANG Xiao-xia LI Guo-qian HONG Zhu-quan,et al.Department of Neurology, Quanzhou First Hospital AffiliatedFujian Medical University, Fujian362000,China

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    【Abstract】 Objective To investigate the efficacy of combined intravenous acutase and edaravone on the patients with acute cerebral infarction. MethodsEighty-one patients with first acute cerebral infarction were assigned to the group treated with acutase and another group treated with a combination of intravenous acutase and edaravone. Control test was performed. ResultsThe efficacy of therapeutic alliance group was better than the acutase alone treated group(P<0.05). NIHSS score decreased significantly in the therapeutic alliance group compared with the acutase alone treated group after thirty days treatment (P<0.05). ConclusionCombined intravenous acutase and edaravone can more effectually diminished the level of neurologic impairment after acute cerebral infarction. ......

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