【摘要】目的 了解本地区淋病奈瑟菌的耐药性，为临床治疗提供实验依据。方法细菌鉴定采用API鉴定条，药敏试验采用K-B法，WHONET5.4软件进行统计分析。 结果 82例淋病奈瑟菌中，产β-内酰胺酶菌株25株，阳性率为30.5%；淋病奈瑟菌对大观霉素、头孢曲松较敏感，对青霉素、环丙沙星耐药严重。 结论青霉素、四环素以及氟喹诺酮类药物已不宜作为本地区治疗淋病的常规药物；大观霉素、头孢曲松可作为治疗淋病的首选药物，同时应加强淋病奈瑟菌的耐药性监测。

    【关键词】淋病奈瑟菌 耐药性

    Analysis on antibiotic resistance of 82 strains of Neisseria gonorrhoeaeBian FengzhiSun YuguoSong BingyueLi Jinwen

    (Department of clinical laboratory, the Fourth Hospital of Jinan, Shandong Jinan250031, China)

    [【Abstract】Objective: To investigate antibiotic resistance of Neisseria gonorrboeae and to provide a guidance to clinical rational use of antibiotics. Methods: Identification of bacteria was performed with API and disc diffusion test (K-B method) was used to study the drug resistance of isolated from clinical source. The date analysis were made with whonet 5.4 software. Result: 25 strains were consideredproducing β-lactamase in 82 strains of Neisseria gonorrhoea ......