右旋美托咪定用于ICU机械通气患者中的临床观察(2)
第1页 |
参见附件。
总之, 右旋美托咪定用于ICU机械通气患者能够保证有效镇静, 减轻患者带管痛苦, 其疗效及安全性可靠。
参考文献
[1]Pandharipande P P, Sanders R D, Girard T D et al. Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis:an a priori-designed analysis of the MENDS randomized controlled trial.Crit Care, 2010,14(2):R38.
[2]Deutsch E.tobias JD Hemodynamie and respiratory changes follow dexmedetomine during general anesthesia:sevoflurane vs desflurane. Paediatr Anaesth, 2007,17(5):438-444.
[3]Dutta S, Karolm D, Cohen T, et al. Effect of dexmedetomine on propofol requirements in healthy subjects. J Pharm Sci, 2009, 90(2):244-254.
[4]Huupponen E, Maksimow A, Lapinlampi P, et al. Electroen-cephalogram spindle activity during dexmedetomidine sedation and physiological sleep. Aeta Anaesthesiol scand, 2008,52(2):289-294.
[5]Chen BS, Peng H, Wu SN. Dexmedetomidine, an 2-adrenergic agonist, inhibits neuronal delayed-rectifier potassium current and sodium current. Br J Anaesth, 2009,103(2):244-254.
[6]Steppan J, Wagner T. Central sympatholytics prolong survival in experimental sepsis. Crit Care, 2009,13(1):R11.
您现在查看是摘要介绍页,详见PDF附件。