吸烟对肺癌患者血清转化生长因子—β1水平的影响(2)
综上所述， 肺癌患者血清中TGF-β1水平较健康人群明显增高， 吸烟患者血清中TGF-β1水平较不吸烟者高。TGF-β1与肺癌的发生有密切关系， 吸烟可导致血清TGF-β1水平升高。
参考文献
[1]Bedossa P， Peltier E， Terris B， et al. Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal， cirrhotic， and neoplastic human livers. Hepatology， 1995， 21(3)：760-766.
[2]Asselin-Paturel C， Echchakir H， Carayol G， et al. Quantitative analysis of Th1， Th2 and TGF-beta1cytokine expression in tumor， TIL and PBL of non-small cell lung cancer patients. Int J Cancer， 1998， 77(1)：7-12.
[3]Clausen E， Wittman C， Gingo M， et al. Chest Computed Tomography Findings in HIV-Infected Individuals in the Era of Antiretroviral Therapy. PLoS One， 2014， 9(11)：e112237.
[4]Pairon JC， Andujar P， Rinaldo M， et al. Asbestos exposure， pleural plaques， and the risk of death from lung cancer. Am J Respir Crit Care Med， 2014， 190(12)：1413-1420.
[5] Kalaivani P， Saranya S， Poornima P， et al. Biological evaluation of new nickel(Ⅱ) metallates： Synthesis， DNA/protein binding and mitochondrial mediated apoptosis in human lung cancer cells (A549) via ROS hypergeneration and depletion of cellular antioxidant pool. Eur J Med Chem， 2014(82)：584-599.
[收稿日期：2015-06-15], http://www.100md.com(郭彩霞)
参考文献
[1]Bedossa P， Peltier E， Terris B， et al. Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal， cirrhotic， and neoplastic human livers. Hepatology， 1995， 21(3)：760-766.
[2]Asselin-Paturel C， Echchakir H， Carayol G， et al. Quantitative analysis of Th1， Th2 and TGF-beta1cytokine expression in tumor， TIL and PBL of non-small cell lung cancer patients. Int J Cancer， 1998， 77(1)：7-12.
[3]Clausen E， Wittman C， Gingo M， et al. Chest Computed Tomography Findings in HIV-Infected Individuals in the Era of Antiretroviral Therapy. PLoS One， 2014， 9(11)：e112237.
[4]Pairon JC， Andujar P， Rinaldo M， et al. Asbestos exposure， pleural plaques， and the risk of death from lung cancer. Am J Respir Crit Care Med， 2014， 190(12)：1413-1420.
[5] Kalaivani P， Saranya S， Poornima P， et al. Biological evaluation of new nickel(Ⅱ) metallates： Synthesis， DNA/protein binding and mitochondrial mediated apoptosis in human lung cancer cells (A549) via ROS hypergeneration and depletion of cellular antioxidant pool. Eur J Med Chem， 2014(82)：584-599.
[收稿日期：2015-06-15], http://www.100md.com(郭彩霞)