青光眼患者局部用药依从性的影响因素及其对视野缺损进展的影响(1)
【摘要】 目的 观察研究青光眼患者局部用药依从性的影响因素， 并分析用药依从性对视野缺损进展的影响。方法 回顾性分析136例青光眼患者的临床资料， 通过问卷调查方式进行研究， 了解患者用药的依从性。观察青光眼患者的一般情况及局部用药依从性的影响因素， 分析青光眼患者局部用藥依从性对视野缺损进展的影响。结果 患者中女80例， 男56例;城市居民86例， 农村居民50例;原发性开角型青光眼70例， 原发性闭角型青光眼36例， 继发性青光眼30例;有青光眼家族史29例， 无青光眼家族史107例;年龄<30岁26例， 30～60岁76例， >60岁34例;初中及以下学历42例， 高中学历66例， 大学及以上学历28例;用1种滴眼液者27例， 用2种滴眼液者57例， 用3种滴眼液者19例， 用4种滴眼液者33例;每日累计点药次数≤3次者77例， 4～6次者21例， >6次者38例。依从性非常好64例， 依从性良好32例， 依从性一般24例， 依从性差16例。不同性别、居住地区、青光眼类型、青光眼家族史患者的用药依从性比较差异无统计学意义(P>0.05);不同年龄、用药种类、累计点眼频次、受教育程度患者用药依从性比较差异具有统计学意义(P<0.05)。依从性非常好患者视野缺损进展8例(12.5%)， 依从性良好患者视野缺损进展6例(18.8%)， 依从性一般患者视野缺损进展7例(29.2%)， 依从性差患者视野缺损进展9例(56.3%)， 比较差异具有统计学意义(χ2=15.190， P<0.05)。结论 临床医师应尽量减少用药的频率及种类， 加强患者的教育， 以提高青光眼患者局部用药的依从性， 减缓视野缺损的进展。
【关键词】 青光眼;用药依从性;视野
DOI：10.14163/j.cnki.11-5547/r.2020.17.015
【Abstract】 Objective To observe the influence factors of local medication compliance in glaucoma patients and analyze its influence on the progress of visual field defect. Methods The clinical data of 136 patients with glaucoma were retrospectively analyzed， and research was conducted through questionnaires to understand the compliance of patients with medication. The general situation of glaucoma patients and the influencing factors of local medication compliance were observe， and the influence of local medication compliance on the progress of visual field defect in glaucoma patients were analyzed. Results There were 80 females and 56 males; 86 urban residents and 50 rural residents; 70 cases of primary open-angle glaucoma， 36 cases of primary angle-closure glaucoma， 30 cases of secondary glaucoma; 29 cases had a family history of glaucoma， 107 cases had no family history of glaucoma; 26 cases were <30 years old， 76 cases were 30-60 years old， 34 cases were> 60 years old; 42 cases were junior high school and below， 66 cases were high school， 28 cases were university or above; 27 cases with 1 kind of eye drops， 57 cases with 2 kinds of eye drops， 19 cases with 3 kinds of eye drops， 33 cases with 4 kinds of eye drops; 77 cases with cumulative daily dispensing times ≤3 times， 21 cases with 4-6 times， and 38 cases with> 6 times. There were 64 cases with very good compliance， 32 cases with good compliance， 24 cases with general compliance and 16 cases with poor compliance. There was no statistically significant difference in drug compliance among patients with different genders， living areas， types of glaucoma and family histories of glaucoma (P>0.05). There was statistically significant difference in drug compliance among patients with different ages， types of medications， cumulative frequency of dropping and education level (P<0.05). There were 8 cases (12.5%) of visual field defect progression in patients with very good compliance， 6 cases (18.8%) of visual field defect progression in patients with good compliance， 7 cases (29.2%) of visual field defect progression in patients with general compliance and 9 cases (56.3%) of visual field defect progression in patients with poor compliance， and the difference was statistically significant (χ2=15.190， P<0.05). Conclusion Clinicians should try their best to reduce the frequency and types of medication， strengthen the education of patients， so as to improve the compliance of local medication of glaucoma patients and reduce the progress of visual field defect., http://www.100md.com(倪宝玲 赵平)
【关键词】 青光眼;用药依从性;视野
DOI：10.14163/j.cnki.11-5547/r.2020.17.015
【Abstract】 Objective To observe the influence factors of local medication compliance in glaucoma patients and analyze its influence on the progress of visual field defect. Methods The clinical data of 136 patients with glaucoma were retrospectively analyzed， and research was conducted through questionnaires to understand the compliance of patients with medication. The general situation of glaucoma patients and the influencing factors of local medication compliance were observe， and the influence of local medication compliance on the progress of visual field defect in glaucoma patients were analyzed. Results There were 80 females and 56 males; 86 urban residents and 50 rural residents; 70 cases of primary open-angle glaucoma， 36 cases of primary angle-closure glaucoma， 30 cases of secondary glaucoma; 29 cases had a family history of glaucoma， 107 cases had no family history of glaucoma; 26 cases were <30 years old， 76 cases were 30-60 years old， 34 cases were> 60 years old; 42 cases were junior high school and below， 66 cases were high school， 28 cases were university or above; 27 cases with 1 kind of eye drops， 57 cases with 2 kinds of eye drops， 19 cases with 3 kinds of eye drops， 33 cases with 4 kinds of eye drops; 77 cases with cumulative daily dispensing times ≤3 times， 21 cases with 4-6 times， and 38 cases with> 6 times. There were 64 cases with very good compliance， 32 cases with good compliance， 24 cases with general compliance and 16 cases with poor compliance. There was no statistically significant difference in drug compliance among patients with different genders， living areas， types of glaucoma and family histories of glaucoma (P>0.05). There was statistically significant difference in drug compliance among patients with different ages， types of medications， cumulative frequency of dropping and education level (P<0.05). There were 8 cases (12.5%) of visual field defect progression in patients with very good compliance， 6 cases (18.8%) of visual field defect progression in patients with good compliance， 7 cases (29.2%) of visual field defect progression in patients with general compliance and 9 cases (56.3%) of visual field defect progression in patients with poor compliance， and the difference was statistically significant (χ2=15.190， P<0.05). Conclusion Clinicians should try their best to reduce the frequency and types of medication， strengthen the education of patients， so as to improve the compliance of local medication of glaucoma patients and reduce the progress of visual field defect., http://www.100md.com(倪宝玲 赵平)
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