平阳霉素碘油乳剂治疗肝血管瘤的疗效评价(1)
 |
| 第1页 |
参见附件(1573KB，2页)。
【摘要】 目的 评价平阳霉素碘油乳剂肝动脉栓塞治疗对肝血管瘤的临床疗效。方法 将43例肝血管瘤患者随机分为对照组21例和观察组22例。对照组选用超液态碘化油5~20 ml与适量造影剂混合制成碘化油乳剂进行栓塞治疗;观察组将平阳霉素8~24 mg溶于2%的利多卡因3~5 ml中,然后与碘化油5~20 ml充分混合制成碘化油乳剂进行栓塞治疗。结果 本组43例患者共行栓塞治疗52次,其中7例在2个月后行第二次栓塞(包括4例无效患者),1例在2~5个月内行第三次栓塞。术后2~6个月复查B超、CT或行肝动脉造影,除3例无效患者外,其余患者肿瘤均有不同程度的缩小。观察组治疗效果明显优于对照组,结果经χ2检验,差异有统计学意义(P<0.05)。结论 平阳霉素碘油乳剂动脉栓塞对肝血管瘤疗效较好,安全可靠,副反应小,可作为首选治疗方法。
【关键词】肝血管瘤;平阳霉素;碘油;栓塞治疗
Efficay evaluation of Pingyangmycin lipiodol emulsion treatment on hepatic hemangioma
CHEN Hui.Radiology departrment of the first people’s hospital ofShanqiu,Henan 476000,China
【Abstract】 Objective To evaluate the pingyangmycin-lipiodol emulsion on hepatic artery embolization for the clinical efficacy of hepatic hemangioma.Methods 43 cases of hepatic hemangioma were randomly divided into control group,(21 cases) and observation group(22 cases).Control group,used ultra-liquid iodized oil 5~20 ml blend with the amount of contrast agent lipiodol emulsion embolization;Observer Group,PYM 8~24 mg dissolved in 2%lidocaine 3~5 ml,and then with the 5~20 ml adequately iodized oil mixture made of iodized oil emulsion embolization.Results A total of 43 patients,embolization therapy 52 times,including seven cases in 2 month after the second embolization(including 4 cases of invalid patients),1 case in the 2 to 5 months,insiders third embolization.After 2 to 6 months follow-B-,CT or hepatic arteriography,in addition to three cases of invalid patients,the remaining tumor in patients with varying degrees of narrowing.Treatment of the observation group was better than the control group,the results by the χ2 test,the difference was statistically significant(P<0.05).Conclusion Pingyangmycin lipiodol emulsion embolization to treat hepatic hemangioma has a good efficacy,safe,side effects,can be used as the preferred method of treatment.
【Key words】Hepatic hemangioma;Pingyangmycin; Lipiodol; Embolization
肝血管瘤是肝脏常见的良性肿瘤,其发病率为4%~7%,其中50%~70%无临床症状[1]。当血管瘤较大或靠近肝脏表面时会出现压迫症状,表现为肝区不适,腹部包块,肝功能降低等,甚至破裂出血,危及患者生命。笔者自2006年1月至2009年3月选用平阳霉素碘油乳剂(Pingyangmycin-Lipiodol emulsion,PLE)栓塞治疗肝血管瘤22例,并对其疗效和并发症进行分析。现将结果总结报道如下。
1 资料与方法
1.1 一般资料 本组肝血管瘤患者43例,术前均经B超、CT和(或)MRI和肝血管DSA确诊。其中男18例,女25例,年龄31~64岁,平均44.7岁。超声检查肿瘤单发34例,其中右叶21例,左叶13例;9例多发,累及肝左、右叶。血管瘤直径4.0~17.7 cm,平均8.2 cm。43例患者按随机原则分为 ......
您现在查看是摘要介绍页，详见PDF附件(1573KB，2页)。