阿托伐他汀对心房快速起搏犬心房电重构的影响(1)
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[摘要] 目的 研究阿托伐他汀对心房快速起搏犬心房电重构的影响。方法 18只犬分为假手术组、对照组和治疗组。对照组和治疗组心房快速起搏8周,治疗组给予每日阿托伐他汀2mg/kg。术前及术后8周测定心房有效不应期(AERP)离散度、心房内传导时间、心房肌传导速度。结果 起搏8周后,与对照组比较,治疗组AERP离散度减小,心房内传导时间缩短,心房肌传导速度加快。结论 阿托伐他汀减轻快速心房起搏犬AERP离散,改善心房电重构。
[关键词] 阿托伐他汀;犬;电重构
[中图分类号] R541.7+5[文献标识码] A [文章编号] 1673-9701(2009)36-13-03
Effect of Atorvastatin on Atrial Electrical Remodeling in Rapid Atrial Pacing Dog
DU Song1 LUO Ping1YUAN Fang1ZHANG Pu2
1.Department of Cardiology,Henan Provincial People’s Hospital,Zhengzhou 450003,China;2.Department of Cardiology,the Fifth Affiliated Hospital of Zhenzhou University,Zhengzhou 450003,China
[Abstract] Objective To investigate the effects of Atorvastatin on atrial electrical remodeling in rapid atrial pacing dogs. Methods Eighteen dogs were devided into sham operation group,control group and Atorvastatin treatment group ......
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