小儿MP感染血清细胞因子\hs-CRP及免疫球蛋白的变化
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[摘要] 目的 探讨检测肺炎支原体(MP)感染患儿血清细胞因子、高敏C-反应蛋白及免疫球蛋白的临床意义。方法 56例MP感染患儿和58例健康儿童为研究对象,测定血清白细胞介素IL-2、IL-6、IL-8、IL-12,hs-CRP和IgA、IgM、IgG。结果 观察组血清IL-2、IL-12和IgA的水平与对照组比较显著降低;观察组血清IL-6、IL-8、hs-CRP、IgM、IgG水平与对照组比较显著上升。结论 检测炎性细胞因子、hs-CRP的变化及血清免疫球蛋白对判定病情和预后有一定的临床应用价值。
[关键词] 肺炎支原体; 血清细胞因子; 高敏C-反应蛋白; 免疫球蛋白
[中图分类号] R725.6 [文献标识码] A [文章编号] 1673-9701(2010)01-22-02
Alteration of Serum Cytokines,High-sensitivity C-reactive Protein and Immunoglobulin in Mycoplasma Pneumonia Infection in Children
HE Shuqing WEN Xinlan XU Na
Department of Pediatrics,PLA No.322 Hospital,Datong 037006,China
[Abstract] ObjectiveTo investigate the clinical significance of the detection of serum cytokines,high-sensitivity C-reactive protein(hs-CRP)and immunoglobulin level in children with mycoplasma pneumoniae(MP) infection. MethodsThere were 56 children with MP infection and 58 healthy children in the present study. The serum IL-2,IL-6,IL-8and IL-12 and hs-CRP and IgA,IgM and IgG were detected. ResultsThe levels of the serum IL-2 andIL-12 and IgA in the observation group were lower than those of the control group ......
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