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布加综合征的临床分析(1)
http://www.100md.com 2011年8月5日 陶利萍 杨晓蕾 吴小丽 黄智铭
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     [摘要] 目的 分析布加综合征的临床特点,以提高对该病的认识,减少误诊。方法 回顾性分析19例布加综合征患者的病史、症状、体征、实验室检查、影像学检查及治疗随访情况。结果 布加综合征患者的职业多为农民及打工者(68.4%),临床表现主要为腹胀(78.9%)、肝脾肿大(占47.4%及63.2%)、侧腹壁静脉曲张(57.9%)、腹水(36.9%)、下肢水肿(26.3%)、下肢静脉曲张、色素沉着或溃疡(31.6%)。彩色多普勒和磁共振血管成像的诊断率达80%和84.6%。16例患者行介入或手术治疗,其中12例介入治疗者测下腔静脉直径由术前(24.58±3.85)mm缩小为(17.92±3.05)mm(P <0.01),下腔静脉压力由术前(3.08±0.38)kPa降为术后(1.89±0.28)kPa(P <0.01)。结论 门脉高压表现重或伴有下腔静脉高压而肝大、肝功能损害轻者,应高度怀疑本病。彩色多普勒和磁共振血管成像是重要的检查方法,早期诊断及治疗对预后有重要的影响。介入手术是有效的治疗手段。

    [关键词]布加综合征; 影像学;误诊;介入;手术

    [中图分类号] R575 [文献标识码] B [文章编号]1673-9701(2011)22-38-03

    Budd-Chiari Syndrome

    TAO Liping1 YANG Xiaolei2 WU Xiaoli1 HUANG Zhiming1

    1. Department of Gastroenterology of the First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China;2. Department of General Practice of the First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China.

    [Abstract] Objective To explore the clinical features of Budd-Chiari syndrome for further understanding of the disease and decreasing the misdiagnosis. Methods Ninteen cases were analyzed retrospectively in history, symptoms, physical sign, laboratory examination, imaging examination, therapy and follow-up. Results Most of the patients were farmers and workers (68.4%). Abdominal distention (78.9%), hepatomegalia (47.4%), splenomegalia (63.2%), subcutaneous varicos vein of latero-abdominal wall (57.9%), ascites (36.9%), edema of lower extremity (26.3%), varicose veins, pigmentation and ulcer of lower extremity (31.6%) was the most common clinical manifestation. The diagnostic coincidence of color Doppler and magnetic resonance angiography reached 80% and 84.6%, respectively. 16 cases accepted interventional therapy or surgical operation and had a good prognosis. The diameter of inderior vena cava in 12 cases who received interventional therapy falled from (24.58±3.85)mm before the operation to( 17 ......

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