化瘀止痛汤联合米非司酮治疗子宫内膜异位症痛经的疗效观察(1)
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[摘要] 目的 探讨化瘀止痛汤联合小剂量米非司酮治疗子宫内膜异位症(Endometriosis，EM)痛经的临床疗效。方法 对92例EM痛经患者随机分为观察组和对照组，对照组于月经第14天开始口服米非司酮片剂6.25mg，每日1次，用药4d。观察组在对照组用药的基础上联合自拟中药化瘀止痛汤，每个月经周期用药4d。两组均3个月经周期用药为1个疗程。结果 治疗3个月后观察组痊愈率25.00%，总有效率93.75%。对照组痊愈率9.09%，总有效率70.45%，两组比较差异有显著性(P<0.01)；治疗前后痛经积分疗效比较，观察组治疗前后比较P<0.01，治疗后观察组与对照组比较P<0.01，说明观察组缓解痛经症状较好。结论 化瘀止痛汤联合小剂量米非司酮治疗EM痛经疗效明显，具有临床应用价值。
[关键词] 子宫内膜异位症(EM)；痛经；化瘀止痛汤；米非司酮
[中图分类号] R711.71 [文献标识码] B [文章编号] 1673-9701(2011)33-42-02
The Efficacy of Huayuzhitong Decoction Combined with Mifepristone in Treatment of Dysmenorrhea Coursed by Endometriosis
NI Xiaojun BAO Lanpin
Department of Gynaceology and Obstetrics，Zhejiang Province Lanxi City Traditional Chinese Medical Hospital，Lanxi 321100，China
[Abstract] Objective To investigate the clinical effectiveness of Huayuzhitong decoction combined with mifepristone for dysmenorrhea coursed by Endometriosis(EM). Methods All of 92 dysmenorrhea patients with confirmed diagnosis of EM were randomly divided into observation group and control group. From the 14th day in menstrual cycle，patients in control group were given mifepristone tablets 6.25mg once per day for 4 days，and patients in observation group were given the same doses of mifepristone combined with self-priscribed Chinese herb medicine Huayuzhitong decoction for 4 days per cycles. Three menstrual cycles was a course of treatment. Results After 3 months of treatment effective rate was 25.00% and total effective rate was 93.75% in the observation group. And in the control group the effective rate was 9.09%，the total effective rate was 70.45%. There was significant difference(P<0.01). Dysmenorrhea score in observation group was decrease after treatment(P<0.01). Dysmenorrhea score in observation group was lower than control group(P<0.01). It indicates observation group was better in relief of dysmenorreha. Conclusion The clinical effectiveness of Huayu zhitong decoction combined with mifepristone for dysmenorrhea coursed by EM is better than mifepristone，and it has clinical value ......
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