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社区患者血糖浓度与糖化血红蛋白、血脂和血液流变学的相关性(1)
http://www.100md.com 2011年12月15日 高颖 周燕雯
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     [摘要] 目的 探讨社区患者血糖浓度与糖化血红蛋白、血脂、血流变升高的相关性。方法 对我院2010年10~12月1870例患者的门诊生化测定的血糖、糖化血红蛋白、血脂及血流变数据进行整理并统计分析,将患者分为血糖正常[(3.9~6.1)mmol/L]、血糖受损[(6.1~7.0)mmol/L]和糖尿病(>7.0mmol/L)三组,观察血糖浓度对糖化血红蛋白、血脂及血流变的影响。结果 糖尿病组、血糖受损组与血糖正常组中糖化血红蛋白、血脂及全血黏度之间的差异有统计学意义(P<0.05),而血沉没有统计学意义(P>0.05)。 结论 高血糖、高血脂以及全血黏度增高均是糖尿病并发动脉粥样硬化独立的危险因素。定期监控有关指标对预防、治疗和减少糖尿病患者并发症的发生具有重要的临床意义。

    [关键词] 社区患者;血糖浓度;糖化血红蛋白;血脂;血液流变学;相关性

    [中图分类号] R587.1 [文献标识码] B [文章编号] 1673-9701(2011)35-09-03

    The Correlation between Blood Glucose Concentration and Glycated Hemoglobin,Lipids and Hemorheology in Community Patients

    GAO Ying ZHOU Yanwen

    The Laboratory Department of Putuo District Yichuan Community Health Center,Shanghai 200065,China

    [Abstract] Objective To investigate the correlation between blood glucose concentration of the community patients and the rise of glycolated hemoglobin, serum lipids and hemorheology. Methods Collected and made a statistic analysis on the data of blood glucose,glycolated hemoglobin,serum lipids and hemorheology measured by biochemistry in 1870 outpatients during October to December,2010 in our hospital. Divided all the patients into normal blood glucose(3.9 to 6.1 mmol/L),impaired fasting glucose(6.1 to 7.0 mmol/L) and diabetes(>7.0 mmol/L)three groups. Observed the influences of blood glucose concentration on glycolated hemoglobin,serum lipids and hemorheology by adopting t-test analysis. Results There were statistical differences in glycolated hemoglobin,serum lipids and whole blood viscosity between diabetes group,impaired fasting glucose group and normal blood glucose group(P<0.05),while there were no statistical differences in erythrocyte sedimentation rate(P>0.05). Conclusion High blood glucose,high serum lipids and the rise of whole blood viscosity are all independent risk factors for diabetic complications of atherosclerosis. Monitoring the related indicators regularly has important clinical significance for preventing,curing and decreasing the occurrence of the complications of diabetics ......

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